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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Comparative clinical pathology 5 (1995), S. 149-157 
    ISSN: 1433-2981
    Keywords: Acute phase index ; Acute phase proteins ; Blood ; Cattle ; Clinical chemistry ; Haematology ; Haptoglobin ; Isolation procedure ; Pig ; SAA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Clinical, zootechnical and industrial developments of the last decades have led to new ideas on monitoring systems for animal production and meat inspection. Quality assessment systems, integrated monitoring, risk assessment concerning consumer's health and monitoring for infectious animal diseases, are more relevant today than pathomorphological control of individual subjects. Published papers on investigations to assess slaughtered animals by blood variables of classical clinical pathology and by measuring acute phase reactants, are mentioned. Most papers deal with ruminants giving good perspectives for the acute phase proteins in that species. Only limited literature is available regarding acute phase proteins in swine; zinc and iron have been shown to be of little value for general health monitoring in swine. Preliminary studies on limited numbers of finishing pigs showed good prospects for the development of species specific assays for acute phase proteins for future practical use in the slaughterhouse. Isolation procedures for porcine haptoglobin (HP), serum amyloid A (SAA) and C reactive protein (CRP) are described. It is suggested that for monitoring individual animals, the signal of acute phase variable can be amplified considerably by applying an acute phase index (API) combining positive × negative reactants−1. Calculations on the original data from a former investigation on 233 nonhealthy and 21 control cattle gave excellent results for an API. Similar studies are in progress for swine.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Virchows Archiv 412 (1987), S. 27-29 
    ISSN: 1432-2307
    Keywords: Restrictive cardiomyopathy ; Endomyocardial fibrosis ; Infiltrative changes of the myocardium ; Intracellular deposits
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Restrictive cardiomyopathy is usually related to fibrosis of the endocardium or to an infiltrative disorder. However, in few cases, it can be due to isolated pathology of the myocytes but such alterations are not well characterized. This paper reports the disease in two 7 year old patients. There was severe venous congestion and catheterisation revealed increased end diastolic pressure in the ventricles. Both pericardial and myocardial biopsies were performed, as the clinical and haemodynamic data were indistinguishable from constrictive pericarditis. The structure of the pericardium was normal. The endocardium was not thickened. The interstitium of the myocardial tissue was not increased. Electron microscopic examination revealed intracellular masses of disorganized myofilaments. These large deposits may have produced decrease compliance of the myocytes and of the ventricular walls.
    Type of Medium: Electronic Resource
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