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  • 1
    ISSN: 1432-2013
    Keywords: Free fatty acids ; Skeletal muscle ; Membrane conductance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract 1. Na-octanoate (in Ringer's solution) affects the membrane resistance of isolated frog skeletal muscle fibres in a biphasic way. Initially there is an increase followed by a more slowly developing decrease. The effect depends on both the concentration of the fatty acid (1–20 mM) and the time of exposure (2–20 min). 2. In muscles exposed either to isotonic K2SO4 or to Ringer's solution with Cl− substituted by methylsulphate, the octanoate-induced resistance drop is the same as in normal Ringer's solution whereas an initial increase is not observed. 3. In Na-free (Tris-) Ringer's solution, only an increase in membrane resistance is caused by octanoate. 4. The results suggest that Na-octanoate decreases the conductance of the resting muscle cell membrane for anions (Cl−) whereas the permeability for cations (Na+, K+) is increased.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 47 (1981), S. 271-279 
    ISSN: 1439-6327
    Keywords: Local rhythmical muscle work ; Rest intervals ; iEMG ; Duration of the R-R interval ; Endurance time ; Recovery time
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In a model work place (hand-grip dynamometer), eleven subjects performed rhythmical hand-grip contractions to exhaustion (frequency 30/min). In each working cycle the contraction and rest phases were distinguished. The work to exhaustion was repeated four times (four working periods with 15-min rest intervals). The tests were performed at 40, 60, 80, 100% MVC. Analysis of Variance showed no difference in the group means (mean values of each working period and load level) for the duration of the contraction or rest phases, the integrated bioelectrical muscle activity (iEMG) of flexors, extensors, brachioradialis (iEMG referred to working cycle and contraction phase) or iEMG of the thenar muscles (referred to the working cycle), or in the duration of the R-R interval in the ECG during comparable periods of the experiments. The endurance times decreased from working period 1–4, and a similar decrease occurred in the force-time product. It may be concluded from these results that 15 min rest is insufficient for adequate recovery from hand-exhaustion exercise.
    Type of Medium: Electronic Resource
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