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  • Engineering General  (6)
  • Nuclear reaction  (4)
  • Gynogenesis  (2)
  • Insulin-regulated glucose transporter GLUT4  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Inelastic scattering of 61 mev protons from ^9^0Zr and ^8^9Y
    Amsterdam : Elsevier
    Nuclear Physics, Section A 181 (1972), S. 417-439 
    Details
    ISSN: 0375-9474
    Keywords: Nuclear reaction
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0375-9474(72)90493-9
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    ^2^0^7Pb(p, p') measurements at 135 and 61 MeV, the effective interaction and core polarization
    Amsterdam : Elsevier
    Nuclear Physics, Section A 366 (1981), S. 91-108 
    Details
    ISSN: 0375-9474
    Keywords: Nuclear reaction
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0375-9474(81)90489-9
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Low-lying normal parity excitations in the ^2^0^8Pb(p, p')^2^0^8Pb reaction at Ep = 61.2 MeV
    Amsterdam : Elsevier
    Nuclear Physics, Section A 285 (1977), S. 222-234 
    Details
    ISSN: 0375-9474
    Keywords: Nuclear reaction
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0375-9474(77)90249-4
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Core polarization in inelastic proton scattering from ^2^0^9Bi at 61 MeV
    Amsterdam : Elsevier
    Nuclear Physics, Section A 226 (1974), S. 109-130 
    Details
    ISSN: 0375-9474
    Keywords: Nuclear reaction
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0375-9474(74)90603-4
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Mutation of two conserved arginine residues in the glucose transporter GLUT4 supresses transport activity, but not glucose-inhibitable binding of inhibitory ligands (1995)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 353 (1995), S. 36-41 
    Details
    ISSN: 1432-1912
    Keywords: Glucose transport ; IAPS-forskolin ; Insulin-regulated glucose transporter GLUT4
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Two arginine residues (RR333/334) in the conserved GRR motif located in the endofacial loop between helix 8 and 9 of the glucose transporter GLUT4 were substituted for leucine and alanine, respectively. Reconstituted glucose transport activity of the construct (GLUT4-RR333/4LA) expressed in COS-7 or LM(TK-) cells was less than 10% of that of the wild-type GLUT4. In contrast, binding of the inhibitory ligand cytochalasin B and glucose-inhibitable photolabeling with IAPS-forskolin were not significantly affected. Exchange of a histidine residue (H337Q) previously believed to be involved in the binding of inhibitory ligands failed to affect any of the investigated parameters. These data suggest that positive charges in the GRR motif at the cytoplasmic surface of the transporter participate in the conformational changes of the carrier protein during the process of facilitated diffusion.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00168913
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  • 6
    Electronic Resource
    Electronic Resource
    Mutation of two conserved arginine residues in the glucose transporter GLUT4 supresses transport activity, but not glucose-inhibitable binding of inhibitory ligands (1995)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 353 (1995), S. 36-41 
    Details
    ISSN: 1432-1912
    Keywords: Key words Glucose transport ; IAPS-forskolin ; Insulin-regulated glucose transporter GLUT4
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Two arginine residues (RR333/334) in the conserved GRR motif located in the endofacial loop between helix 8 and 9 of the glucose transporter GLUT4 were substituted for leucine and alanine, respectively. Reconstituted glucose transport activity of the construct (GLUT4-RR333/4LA) expressed in COS-7 or LM(TK–) cells was less than 10% of that of the wild-type GLUT4. In contrast, binding of the inhibitory ligand cytochalasin B and glucose-inhibitable photolabeling with IAPS-forskolin were not significantly affected. Exchange of a histidine residue (H337Q) previously believed to be involved in the binding of inhibitory ligands failed to affect any of the investigated parameters. These data suggest that positive charges in the GRR motif at the cytoplasmic surface of the transporter participate in the conformational changes of the carrier protein during the process of facilitated diffusion.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00168913
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Sex determination in the genus Oreochromis (1991)
    Springer
    Theoretical and applied genetics 82 (1991), S. 144-152 
    Details
    ISSN: 1432-2242
    Keywords: Sex determination ; Oreochromis niloticus ; Gynogenesis ; Sex reversal ; Triploidy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Established techniques of genetic manipulation were used to elucidate sex-determining mechanisms in the commercially important tilapia, Oreochromis niloticus. Analysis of sex ratios from single-pair matings of normal broodstock showed these to be heterogeneous, with an asymmetrical frequency distribution. Data were homogeneous, with the exclusion of a number of broods with sex ratios not significantly different from 3∶1 (male: female), and further progeny testing revealed atypical female heterogamety in the parents of these broods. Analysis of sex ratios from complete diallele-type crosses using five males and five females demonstrated no association between male parent, female parent and progeny sex ratio. Sex ratios of gynogens (0∶1) and triploids (1∶1), and from progeny testing of sex-reversed males (0∶1) and sex-reversed females (3∶1), provide evidence for female homogamety in this species. Progeny testing of male gynogens derived from sex-reversed females demonstrated recombination between the centromere and the sex-determining locus (68.9%). Novel YY “supermales” were shown to be viable and produced all-male offspring. It was concluded that this species exhibits monofactorial, genotypic sex determination with male heterogamety. However, rare autosomal or environmental sex-modifying factors may account for occasional deviations from expected sex ratios.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00226205
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  • 8
    Electronic Resource
    Electronic Resource
    Sex determination in the genus Oreochromis (1991)
    Springer
    Theoretical and applied genetics 82 (1991), S. 153-160 
    Details
    ISSN: 1432-2242
    Keywords: Sex determination ; Oreochromis aureus ; Gynogenesis ; Sex reversal ; Hybridisation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Sex ratios from 62 single-pair matings of normal broodstock O. aureus were highly heterogeneous with an overall deficit of males (41.4%). Peaks in the sex ratio frequency distribution occurred at 1∶1, 3∶5 and 1∶3 (male∶female). Hybridisation of O. aureus with O. mossambicus, O. spilums and O. niloticus produced highly variable sex ratios, suggesting a complexity of hybrid sex determination. Few valid inferences could be made regarding intraspecific sex determination from these hybrid data. Sex ratios from progeny testing of sex-reversed males (1∶3) and most sex-reversed females (1∶0) provide evidence for female heterogamety in O. aureus. Several aberrant ratios observed suggest Mendelian inheritance of an autosomal recessive gene (F,f), epistatic to the major sex-determining gene (W,Z). Sex ratios of triploids and gynogens support the hypothesis of recombination between the centromere and the major sex-determining locus. Progeny testing of a female mitogyne demonstrated the viability of a novel WW “superfemale”, which gave only female offspring. Not all data could be explained by a two-factor model of sex determination. Further exceptional sex ratios may be accounted for by rare autosomal or environmental sex-modifying factors. It is concluded that O. aureus has a multifactorial mechanism of sex determination with the underlying primary mechanism of female heterogamety.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00226206
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  • 9
    Electronic Resource
    Electronic Resource
    Generalized geometric programming with many equality constraints (1987)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 24 (1987), S. 725-741 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: A monomial treatment for solving mixed equality/inequality constrained generalized geometric programs is presented. The method is shown to be equivalent to a Newton-Raphson procedure carried out in log space on the equality constraints at the same time that a cutting plane procedure is performed on a convex region constrained within the feasible region of the inequality constraints. Known limitations of this monomial treatment are outlined and a technique for improving the efficiency of the GGP method is suggested. A discussion of how other methods of solving mixed equality/inequality constrained GGP problems compare to the monomial treatment is presented and two example problems are solved.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620240406
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  • 10
    Electronic Resource
    Electronic Resource
    A finite element algorithm for elliptical equations over unstructured domains on a data parallel computerComputational resources were provided by Sandia National Laboratories, Albuquerque, New Mexico and Los Alamos National Laboratories, Los Alamos, New Mexico. (1994)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 37 (1994), S. 3153-3167 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: In the past, most finite element algorithms on data-parallel computers have been limited to structured problem domains. Here, we consider methods to generalize the finite element method on data-parallel architectures to unstructured domains. A nodal assembly algorithm is described which effectively allows for both the generation of the sparse interaction matrix (coefficient matrix) and its solution via a preconditioned conjugate-gradient type routine utilizing several polynomial preconditioners on the Connection Machine 200 (CM-200). Jacobi preconditioning along with Neumann series and least-squares polynomial preconditioners are presented and implemented are presented and implemented. Only the Jacobi preconditioner produces an improvement in the convergence time for the problems examined. Several irregular interprocessor communication protocols available on the CM-200 are investigated in the solution portion of the algorithm, yielding differing performance characteristics. For one such protocol, sustained performance of over two-hundred MFlops/s, is demonstrated for a test problem on a 512 processing element CM-200 in slicewise mode. The results are discussed and conclusions are drawn concerning this finite element algorithm.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620371809
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