ISSN:
1432-0827
Keywords:
Age
;
Bone culture
;
Calcium
;
Phosphate
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
,
Physics
Notes:
Abstract Calvaria taken from mice aged 0, 1, 3 and 5 days were cultured for 48 h, in control medium (no added hormone), or in the presence of PTH (0.5 U/ml) or CT (50 mCl/ml). In the control group, there was a shift from net uptake of Ca and P (0- and 1-day bones) to net release (5-day bones). CT-treated bones of all ages took up Ca from the culture medium, but the percentage uptake declined with increasing age. Bones exposed to PTH released Ca and P to the culture medium, regardless of age. The changes with increasing age may be related to an increase in mineralization and other aspects of maturation in these bones.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02008215
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