ISSN:
0268-2605
Keywords:
Estradiol receptor assays
;
metal carbonyl units
;
cold bioprobes
;
selectivity
;
propargylation
;
cobalt carbonyl
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Introduction of the propargyl dicobalt hexacarbonyl moiety onto the estradiol A ring as a potential probe in receptor studies requires protection of the ring phenolic group, and the regio-selectivity of the attack (2- versus 4-position) depends on the bulkiness of the organometallic carbenium ion.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/aoc.590010509
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