Electronic Resource
Springer
Research in experimental medicine
178 (1980), S. 65-70
ISSN:
1433-8580
Keywords:
Alkaline phosphatase
;
Brush border
;
Ethanol
;
Intoxikation by ethanol
;
Small intestine
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Single administration of ethanol or alcoholic beverages (5 g ethanol/kg body weight) induces a decrease of the 24 h excretion of fecal intestinal alkaline phosphatase (I-AP) activity of 28% (P〈0.05) in comparison to controls (0.9% saline). Administration of higher amounts of 20% (v/v) ethanol (8 g/kg body weight on 3 consecutive days) yields a decrease of fecal I-AP excretion up to 82% (P〈0.005) in comparison to controls (saturated glucose solution). The interpretation of these results as a toxic effect of ethanol to small intestinal mucosa was supported by measurement of enzymatic activity in the small intestinal mucosa and by morphometric data.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01856759
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