ISSN:
1432-0584
Keywords:
Factor XIII deficiency
;
Recurrent abortion
;
Pregnancy
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary A syndrome of marked fetal wastage is associated with congenital factor XIII deficiency in adult women. A previously unreported case of a woman with factor XIII deficiency is described, in which substitutive treatment with normal plasma or placental factor XIII concentrate permitted two normal pregnancies. Factor XIII activity was maintained above 1–2% with intermittent infusion of 300 ml to 450 ml of plasma every 14 days or of 500 units of concentrate every 21 days. This case confirms the only other case so far reported in which factor XIII substitutive therapy was able to permit a normal pregnancy in a woman with factor XIII deficiency and seems to suggest factor XIII to be involved in the process of annidation.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00319641
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