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  • translation inhibition  (2)
  • Frameworks  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Objektorientierte Entwurfsmuster und Frameworks in der Informatik-Ausbildung an der Fachhochschule Konstanz (1997)
    Springer
    Informatik-Spektrum 20 (1997), S. 364-371 
    Details
    ISSN: 1432-122X
    Keywords: Schlüsselwörter  Erfahrung ; Güte ; Softwareengineering ; Entwurfsmuster ; Frameworks ; Informatik-Ausbildung ; Objektorientierung ; C++ ; Java ; GUI-Klassenbibliothek ; Key words  Experience ; quality ; software engineering ; design pattern ; frameworks ; computer science education ; object orientation ; C++ ; Java ; GUI class library ; Computing Reviews Classification  D.1.5 ; D.2.1 ; K.3.2
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Description / Table of Contents: Summary   Design patterns and frameworks, two quite new concepts, allow the reuse of design and of individual design experience. A design pattern embodies local design experience that is related to a few classes, whereas a framework embodies a global kind of experience that covers essential aspects of an application. This article describes experiences with these advanced object-oriented concepts in computer-science education. Concrete examples from projects show how design patterns were successfully used by inexperienced students for designing parts of frameworks. The very positive experiences strongly encourage the inclusion of design patterns and frameworks into computer science education.
    Notes: Zusammenfassung   In den letzten Jahren wurden zwei Konzepte entwickelt, welche die Wiederverwendung von Entwurfserfahrung erlauben. Dies sind zum einen Entwurfsmuster, welche lokale, sich jeweils auf wenige Klassen beziehende Entwurfserfahrung zur Wiederverwendung durch andere Entwickler verfügbar machen, zum anderen Frameworks. Diese erlauben die Wiederverwendung einer globalen Art von Entwurfserfahrung, welche wesentliche Aspekte einer Anwendung umfaßt. Dieser Artikel erläutert Erfahrungen mit Entwurfsmustern bei der Frameworkentwicklung. An einem Beispielprojekt erläutert er die erfolgreiche Arbeit von Studenten mit diesen Methoden. Das Ergebnis ermuntert zur Aufnahme entsprechender Methoden in die Informatiker-Ausbildung.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002870050081
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Relationships between proteasomes and RNA (1995)
    Springer
    Molecular biology reports 21 (1995), S. 43-47 
    Details
    ISSN: 1573-4978
    Keywords: proteasomes ; prosomes ; proteasomal RNA ; translation inhibition ; RNase activity ; RNase E
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The 20S proteasome (prosome) is a highly organized multi-protein complex with approximate molecular weight of about 700 kDa. Whilst the role of the proteasome in the processing and turnover of cellular proteins is becoming clearer, its relationship with RNA remains obscure. Over the last decade the possibility of association of proteasomes with specific RNAs or mRNPs have been particularly controversial. Proteasomes were reported to inhibit translation of viral mRNAs and to be tightly associated with RNase activity. It is possible that proteasomes are also involved in cellular RNA breakdown and RNA processing like prokaryotic RNase E.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00990969
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Proteasomes (prosomes) inhibit the translation of Tobacco mosaic virus RNA by preventing the formation of initiation complexes (1994)
    Springer
    Molecular biology reports 20 (1994), S. 57-61 
    Details
    ISSN: 1573-4978
    Keywords: proteasomes ; prosomes ; Tobacco mosaic virus RNA ; translation inhibition ; initiation complexes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Proteasomes (prosomes) are large multiprotein complexes. They are involved in protein degradation of ubiquitin-conjugated proteins and in the generation of MHC class I peptides. We gave further evidence that they interfere within vitro protein synthesis. Proteasomes inhibit the translation of Tobacco mosaic virus RNA. Analysis of cell-free systems by sucrose gradient centrifugation revealted that they prevent the formation of 80S initiation complexes but not the early phase of initiation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00996354
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    Paper (German National Licenses)
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