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  • GABAA receptor  (1)
  • Ion selectivity  (1)
  • Jacobian-inertia product  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    FEBS Letters 318 (1993), S. 145-148 
    ISSN: 0014-5793
    Keywords: Calcium channel ; Inorganic blocker ; Ion selectivity ; Site-directed mutagenesis ; cDNA expression
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of intelligent and robotic systems 28 (2000), S. 231-258 
    ISSN: 1573-0409
    Keywords: kinematically redundant manipulators ; torque-optimality ; singularity-robustness ; dynamic control equation ; weighted generalized inverses ; Jacobian-inertia product ; damped least-squares inverses ; generalized dynamic manipulability measure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract A new control method for kinematically redundant manipulators having the properties of torque-optimality and singularity-robustness is developed. A dynamic control equation, an equation of joint torques that should be satisfied to get the desired dynamic behavior of the end-effector, is formulated using the feedback linearization theory. The optimal control law is determined by locally optimizing an appropriate norm of joint torques using the weighted generalized inverses of the manipulator Jacobian-inertia product. In addition, the optimal control law is augmented with fictitious joint damping forces to stabilize the uncontrolled dynamics acting in the null-space of the Jacobian-inertia product. This paper also presents a new method for the robust handling of robot kinematic singularities in the context of joint torque optimization. Control of the end-effector motions in the neighborhood of a singular configuration is based on the use of the damped least-squares inverse of the Jacobian-inertia product. A damping factor as a function of the generalized dynamic manipulability measure is introduced to reduce the end-effector acceleration error caused by the damping. The proposed control method is applied to the numerical model of SNU-ERC 3-DOF planar direct-drive manipulator.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1106
    Keywords: Accessory optic system ; GABAA receptor ; Microinjection ; Optokinetic nystagmus ; Chicken
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The SR 95531, a GABAA antagonist was microinjected into either the pretectum nuclei, (nucleus Superficialis Synencephali nSS) or the nBOR (nucleus Ectomammillaris nEM) of chickens. Monocular optokinetic nystamus (OKN) of each eye was recorded by the search coil technique before and after unilateral intracerebral drug administration. Before injection, monocular horizontal OKN in chickens, as in other lower vertebrates, displays a directional asymmetry: the stimulation in the Temporo-Nasal (T-N) direction is more efficient in evoking OKN than is stimulation in the Naso-Temporal (N-T) direction. Unilateral microinjections of SR 95531 into either the nSS or nEM induce a reversible increase of gain in OKN directed by the contralateral eye for both directions of stimulation. However administration into the nSS increased directional asymmetry by increasing the T-N component slow phase velocity more strongly than the N-T component slow phase velocity. On the other hand, the unilateral administration of the drug into the nEM suppressed the directional OKN asymmetry by increasing the N-T component slow phase velocity more strongly than the T-N component slow phase velocity. These results indicate that the drug suppresses GABAergic inhibition at the mesencephalic level. Moreover the nSS seems especially involved in monocular OKN in response to a T-N stimulation, while the nEM seems more involved in the OKN response to N-T stimulation. The increase in gain of OKN directed by the ipsilateral eye to microinjected nuclei could account for the strong interactions existing between these mesencephalic structures responsible for horizontal OKN.
    Type of Medium: Electronic Resource
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