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  • 1
    Electronic Resource
    Electronic Resource
    Application of a GIS-based stream buffer generation model to environmental policy evaluation (1993)
    Springer
    Environmental management 17 (1993), S. 817-827 
    Details
    ISSN: 1432-1009
    Keywords: Environmental policy evaluation ; Geographic information systems ; GIS ; Riparian environmental buffer ; Decision support
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract In this article a GIS method is presented for riparian environmental buffer generation. It integrates a scientifically tested buffer width delineation model into a GIS framework. Using the generally available data sets, it determines buffer widths in terms of local physical conditions and expected effectiveness. Technical burdens of data management, computation, and result presentation are handled by the GIS. The case study in which the method was used to evaluate the stream buffer regulations in a North Carolina county demonstrates its capability as a decision support tool to facilitate environmental policy formulation and evaluation, and environmental dispute resolution.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02393902
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Detection of Hepatitis B Virus Surface Antigen Mutants in Paraffin-Embedded Hepatocellular Carcinoma Tissues (2000)
    Springer
    Virus genes 20 (2000), S. 263-267 
    Details
    ISSN: 1572-994X
    Keywords: hepatitis B virus ; hepatitis B virus surface antigen ; viral DNA isolation ; mutations ; hepatocellular carcinoma ; paraffin-embedded tissue
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The antigenic “a” determinant of the human hepatitis B virus surface antigen (HBsAg) is highly conserved and involved in inducing neutralizing antibody. Mutations on this determinant have been associated with the hepatitis B virus (HBV) escape from vaccination but are also found in chronic HBV carriers, but their involvement in liver diseases including hepatocellular carcinoma (HCC) is unclear. To investigate the possible liver disease-associated role of HBsAg mutants, their incidence was analyzed in 11 paraffin embedded HCC tissues using an improved DNA extraction method. Mutations on the “a” determinant (Thr126Ser, Gly145Arg, a double mutant Thr126Ser/Gln129Asn, Met133Leu and Thr140Ile) were identified in 5 samples while the wild type sequence was found in 2 others. Future characterization of these HCC-associated HBsAg mutants should provide new insights on their role in the pathogenesis of HCC.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008100930584
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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