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  • 1
    ISSN: 1432-1939
    Keywords: Dioecy ; Ephedra trifurca ; Plant-insect interactions ; Gall midges ; Sex-biased herbivory
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract We examined patterns of herbivory in the dioecious desert shrub, Ephedra trifurca (Ephedraceae), along a small watershed in the northern Chihuahuan Desert. We documented significant (p=0.002) sexual dimorphism in densities of Lasioptera ephedrae and L. ephedricola (Diptera: Cecidomyiidae), with male E. trifurca supporting higher densities than did females. Densities of gall midges varied significantly (p〈0.001) among four sample populations of E. trifurca arrayed along the watershed and exhibited an inverse gradient with elevation. There was also a significant (p=0.006) sex-by-site interaction such that the degree of intersexual variation in gall densities decreased down the watershed. Variation in gall densities and intersexual variation in gall densities exhibited inverse trends with variation in soil water and inorganic nitrogen concentrations along the watershed.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1440
    Keywords: Induction ; p53 ; WAF1/CIP1 ; CLL
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The treatment of chronic lymphocytic leukemia includes the use of alkylating agents, steroids, and more recently nucleoside analogues. While prior studies have described potential mechanisms of 2-chlorodeoxyadenosine cytotoxicity including the accumulation of DNA strand breaks and induction of apoptosis or programmed cell death, the expression of p53 and its downstream target WAF1/CIP1 have not been examined. In this report we describe the induction of p53 and WAF1/CIP1 in the apoptotic chronic lymphocytic leukemia cells after exposure to 2-chlorodeoxyadenosine.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1440
    Keywords: Key words Induction ; p53 ; WAF1/CIP1 ; CLL
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  The treatment of chronic lymphocytic leukemia includes the use of alkylating agents, steroids, and more recently nucleoside analogues. While prior studies have described potential mechanisms of 2-chlorodeoxyadenosine cytotoxicity including the accumulation of DNA strand breaks and induction of apoptosis or programmed cell death, the expression of p53 and its downstream target WAF1/CIP1 have not been examined. In this report we describe the induction of p53 and WAF1/CIP1 in the apoptotic chronic lymphocytic leukemia cells after exposure to 2-chlorodeoxyadenosine.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
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