ISSN:
1432-041X
Keywords:
Key words Rhombomere
;
connexin31
;
Gap junctions
;
Communication compartment
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract During segmentation of the mouse hindbrain (d8.0–8.5 pc), expression of the gap junction gene connexin31 (cx31) is precisely restricted to rhombomeres (r) 3 and 5. Shortly afterwards, during the turning process, cx31 expression in rhombomere 3 decreases and is no longer detectable at d9.5 pc, whereas expression in rhombomere 5 is maintained until about d10.0 pc. So far, cx31 is the first gap junction gene found to be expressed in rhombomeres. Its precise segmental and temporal expression pattern may reflect a critical requirement of cx31 channels for these odd numbered rhombomeres to acquire distinct cell identities.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s004270050123
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