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  • General Chemistry  (4)
  • 1
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für die chemische Industrie 96 (1984), S. 556-565 
    ISSN: 0044-8249
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Die mikrobielle asymmetrische Reduktion von Ketonen wird sehr oft zur Herstellung chiraler Alkohole benutzt. Dieser Fortschrittsbericht beschäftigt sich mit den Gesetzmäßigkeiten, die der Enantioselektivität von Enzymen und intakten Zellen zugrundeliegen. Es werden Strategien zur Steuerung des stereochemischen Verlaufs mikrobieller Reduktionen und die Beziehung zwischen Substratstruktur und Enantioselektivität diskutiert.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für die chemische Industrie 101 (1989), S. 711-724 
    ISSN: 0044-8249
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Die enantioselektive Biokatalyse in nicht-wäßrigen Medien gewinnt in der präparativen Chemie zunehmend an Bedeutung. Dieser Beitrag beschreibt a) die generellen katalytischen Eigenschaften von Enzymen in nicht-wäßriger Umgebung, b) die grundlegenden Prinzipien der Herstellung optisch aktiver Carbonsäuren und Alkohole durch Lipase-katalysierte enantioselektive Veresterungen und Umesterungen in organischen Medien, c) die Bestimmung kinetischer und thermodynamischer Parameter und d) die quantitative Analyse von veröffentlichten Daten.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Angewandte Chemie International Edition in English 23 (1984), S. 570-578 
    ISSN: 0570-0833
    Keywords: Asymmetric catalysis ; Catalysis ; Enantioselectivity ; Reduction ; Ketones ; Synthetic methods ; Biotechnology ; Alcohols ; Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Microbial asymmetric reduction of ketones is a method widely used for the preparation of chiral alcohols. The present progress report deals with the basic concepts that govern enantioselectivity of enzymes and intact cells. Strategies to control the stereochemical course of microbial reductions of carbonyl compounds and the relationship of substrate structure to enantioselectivity are considered.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Angewandte Chemie International Edition in English 28 (1989), S. 695-707 
    ISSN: 0570-0833
    Keywords: Enantioselectivity ; Lipases ; Synthetic methods ; Enzyme catalysis ; Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Enantioselective biocatalysis in nonaqueous media is becoming increasingly important in preparative synthetic chemistry. This article discusses (1) the general catalytic properties of enzymes in nonaqueous environments, (2) the basic principles that govern lipase-catalyzed enantioselective esterification and transesterification reactions in organic media for the preparation of optically active acids and alcohols, (3) the determination of kinetic and thermodynamic parameters, and (4) the quantitative analysis of published data.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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