ISSN:
1573-739X
Keywords:
Chromatography, high pressure liquid
;
Derivatization
;
Detection, ultraviolet
;
Gentamicins
;
Microbiological assay
;
o-Phthalaldehyde
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract The content of gentamicin in pharmaceuticals is measured by the high pressure liquid Chromatographic technique described in the monographs for Gentamicin Sulphate and Gentamicin Injection in the British Pharmacopoeia 1980 for the determination of the composition of gentamicin. Calculation procedures are presented to transform this qualitative high pressure liquid Chromatographic procedure for the assay of gentamicin so that it gives results in terms of potency. A comparison is made of this data with the results of the microbiological assay according to the European Pharmacopoeia.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02219666
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