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  • Glucose reabsorption  (1)
  • TmPAH  (1)
  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Pflügers Archiv 369 (1977), S. 79-84 
    ISSN: 1432-2013
    Schlagwort(e): Renal denervation ; Sodium excretion ; Glucose threshold ; Glucose reabsorption
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The effects of acute intravenousd-glucose (G) loading were studied on anaesthetized, unilaterally splanchnicotomized (“renal denervation”) dogs. Glomerular filtration rate (GFR) was generally not different on the innervated and denervated side, while urine flow (V), sodium excretion (UNaV) and urinary excretion (UGV) of glucose on the splanchnicotomized side were significantly increased at any plasma G concentration. Tubular reabsorption (TG) as well as Tm of G in denervated kidneys was considerably depressed. In a series of experiments with moderately elevated plasma glucose level glucosuria on the sympathectomized side was found that seems to be the consequence of a lower threshold for G in denervated kidneys. The positive correlation between the tubular reabsorption of Na and G was not influenced by renal denervation.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Pflügers Archiv 367 (1977), S. 287-290 
    ISSN: 1432-2013
    Schlagwort(e): Renal denervation ; Sodium excretion ; Para-aminohippuric acid secretion ; TmPAH
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Renal excretion of para-aminohippuric acid (PAH) was studied during PAH loading on unilaterally splanchnicotomized (“denervated”) anaesthetized dogs. Urine flow, sodium excretion of denervated kidneys were significantly increased. Below a plasma concentration of 20 mg% there were no differences between intact and denervated kidneys in urinary excretion and in calculated tubular transport of PAH. However, maximum secretion rate on the splanchnicotomized side was significantly decreased (innervated: 34.8, denervated: 25.2 mg/100 ml GFR, respectively). Although both Na reabsorption and PAH secretion are impaired by denervation, the exact mechanism of action of renal sympathectomy is not elucidated as yet.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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