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  • 1
    Electronic Resource
    Electronic Resource
    Transgenic strategies in reproductive endocrinology (1993)
    New York, NY [u.a.] : Wiley-Blackwell
    Molecular Reproduction and Development 34 (1993), S. 337-347 
    Details
    ISSN: 1040-452X
    Keywords: Müllerian-inhibiting substance ; Gonadotropin-releasing hormone ; Glycoprotein hormones ; Growth hormone ; Insulin-like growth factors ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: The present discussion surveys some of the recently published studies utilizing transgenic strategies to address questions in reproductive endocrinology. Beginning with a brief introduction of the transgenic method itself, the following areas are covered: 1. Sexual development and Müllerian-inhibiting substance; 2. Hypogonadal mice and hypothalamic GnRH; 3. The GnRH neuron: generation of immortalized rare cell types; 4. Glyco-protein hormones: immortalized cells, development and evolution; 5. Growth hormone and reproduction; and, 6. Gestation and the insulin-like growth factors. In each section, the discussion attempts to be integrative with respect to the significance of the results to physiological, cellular and molecular biology. We believe this approach is appropriate, as transgenic science itself is necessarily an integration of all of these levels of investigation and participation from those working at all levels is needed. © 1993 Wiley-Liss, Inc.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/mrd.1080340315
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Effect of compounds structurally related to taurine and of taurine uptake inhibitors on the motility of hamster sperm in vitro (1983)
    New York, NY : Wiley-Blackwell
    Gamete Research 7 (1983), S. 347-350 
    Details
    ISSN: 0148-7280
    Keywords: Taurine-related compounds ; taurine antagonists ; taurine uptake inhibitors ; fertilization in vitro ; hamster ; spermatozoa ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: Several taurine-related compounds, taurine antagonists and taurine uptake inhibitors were tested for their effect on hamster sperm motility in vitro. Hypotaurine was approximately three times more effective than taurine. N-methyltaurine and taurocyamine were less effective. Inactive taurine-related compounds were not effective blockers of taurine's spermtimulating activity. However, 1-(4-nitrophenyl)-2-dimethylaminomethyl-l-propenone, a taurine uptake inhibitor, completely suppressed sperm motility at a molar concentration equal to, or less than, that of the taurine added to the incubation medium and also suppressed the motility-sustaining action of the cumulus oophorus.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/mrd.1120070406
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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