ISSN:
1432-0584
Keywords:
Acute lymphoblastic leukemia
;
Granular lymphoblasts
;
Eosinophilia
;
Hypereosinophilic syndrome
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
9 /l), features of hypereosinophilic syndrome, and acute lymphoblastic leukemia (ALL-L2), the latter characterized by the presence of granular blasts. Blasts were negative for myeloperoxidase, non-specific esterase, acid phosphatase, periodic-acid Schiff stain, and toluidine blue. They exhibited an early pre-B immunophenotype (TdT, CD19, CD10, CD20 and CD22 positive) and stained negative for T (CD7, CD2, CD5 and CD3) and myeloid markers (MPO, CD33 and CD13). Chromosomal analysis revealed a normal karyotype. To the best of our knowledge, this case represents the first report of the coexistence of granular ALL and hypereosinophilic syndrome.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s002770050592
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