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  • 1
    Electronic Resource
    Electronic Resource
    Effect of interleukin-2 on the manifestation and growth of acetoxymethyl-methylnitrosamine-induced colorectal rat adenocarcinoma (1986)
    Springer
    Journal of cancer research and clinical oncology 111 (1986), S. 79-81 
    Details
    ISSN: 1432-1335
    Keywords: Acetoxymethyl-methyl-nitrosamine ; Colorectal Rat Adenocarcinoma ; Interleukin-2 ; Lymphoproliferation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of highly purified human interleukin-2 (IL-2) was assessed on acetoxymethyl-methylnitrosamine (AMMN)-induced colorectal Sprague-Dawley rat adenocarcinoma. Treatment was given for 5 weeks and started 5 weeks after a period of 10 weeks intrarectal administration of 2 mg/kg of AMMN once a week. Animals which showed no evidence of tumors by endoscopical examination of the gut were given 10,000 units/kg of IL-2 s.c. into the dorsal region 5 days a week. Blood samples were analyzed from half of the animals before and 72 h after the end of the treatment. The median tumor volume and the median tumor number per rat were lower in the treated group than in the control. A significant decrease in response to two mitogens (PHA, Con-A) was seen in tumor-bearing rats concomitantly with the tumor growth. The immunological suppression was not restored by treatment with IL-2. No differences in natural killer activity or interferon levels were detected between the control and the treated group. These data indicate some antitumor effect of IL-2 given before the manifestation of tumors in AMMN-induced colorectal rat adenocarcinoma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00402782
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    A gas-solid chromatographic study of the adsorption of hydrocarbons and alcohols on graphite (1987)
    Springer
    Chromatographia 23 (1987), S. 97-101 
    Details
    ISSN: 1612-1112
    Keywords: Gas solid chromatography ; Adsorption studies ; Graphite ; Hydrocarbons ; Alcohols
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary The Henry's law region of the adsorption isotherms for several hydrocarbons and alcohols on a graphite was studied by gas-solid chromatography. The thermodynamic functions at zero surface coverage were determined. The low heats of adsorption indicate a highly homogeneous surface. A constant increment of the standard free energy with the number of carbon atoms in the lineal adsorbates was found. Attemps were made to estimate the London contribution to the surface free energy of the adsorbents. A non-specific interaction between the graphite and the adsorbates was shown.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02312881
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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