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  • 1
    Electronic Resource
    Electronic Resource
    HBV, HDV and HIV infections in 242 drug addicts: Two-year follow-up (1988)
    Springer
    European journal of epidemiology 4 (1988), S. 318-321 
    Details
    ISSN: 1573-7284
    Keywords: Hepatitis B ; Hepatitis delta ; Human immunodeficiency virus ; Drug addicts
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Of 242 north Italian heroin addicts, 24 (9.9%) were HBsAg positive. HBeAg was positive in two of them (8.3%), anti-HBe in 16 (66.6%) and anti-HDV in 21 (87.5%). Of the 218 HBsAg negative, 182 (83.5%) had anti-HBc, 72 (33.0%) anti-HBe and 97 (44.5%) anti-HBs. One-hundred-eighty-five drug addicts were anti-HIV positive (76.4%); 77 of these (41.6%) were asymptomatic, 93 (50.3%) had PGL and 15 (8.1%) ARC. T4+ cell count was significantly lower in subjects with ARC as was T4+/T8+ ratio in subjects with PGL and ARC. During a median follow-up of 9.5 months (range 4–25), we observed three new cases of hepatitis (two caused by NANBV and one by HBV with HDV coinfection) and one new HIV infection. Ten anti-HIV positive subjects developed PGL and one AIDS.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00148917
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Prevalence of HIV infection in 646 heroin addicts and outcome of HIV-related conditions in the 266 followed up (1991)
    Springer
    European journal of epidemiology 7 (1991), S. 83-87 
    Details
    ISSN: 1573-7284
    Keywords: HIV ; Hepatitis B ; Hepatitis delta ; Heroin users ; AIDS-related complex (ARC) ; AIDS
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In a series of 646 heroin addicts anti-HIV was detected in 428 (66.2%) and HBsAg in 53 (8.2%). Forty-eight (90.5%) of the latter had concomitant chronic HDV infection. Markers of past HBV infection were found in 481 (74.4%). The prevalence of anti-HIV was significantly higher in the 534 subjects with HBV markers than in the other 112 without markers (69.8% versus 49.1%, p 〈 0.001). Of the 266 anti-HIV positive subjects followed for 3–48 months (median 12), nine progressed from no disease to persistent generalized lymphadenopathy (PGL), 52 from PGL to AIDS-related complex (ARC) or AIDS (30 and 22 cases respectively), and six from ARC to AIDS. Baseline T4 + cell count was significantly lower and reduction during follow-up significantly greater in heroin addicts with disease progression than in those without.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00221346
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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