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  • 1
    Electronic Resource
    Electronic Resource
    Obstetrical management in diabetic pregnancy: the Copenhagen experience (1986)
    Springer
    Diabetologia 29 (1986), S. 13-16 
    Details
    ISSN: 1432-0428
    Keywords: Diabetic pregnancy ; fetal monitoring ; obstetrical management ; Caesarean section
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The outcome of 223 pregnancies in Type 1 (insulin-dependent) diabetic women managed from 1981 to 1985 in the Centre for Pregnant Diabetics in Copenhagen is presented. There were 17 spontaneous and 9 induced abortions. The latter were all done on medical indications. Among the 201 infants weighing 1000 g or more (including 4 pairs of twins), three died perinatally, 2 with lethal congenital malformations and one was stillborn in the 32nd gestational week. This represents a perinatal mortality rate of 2 percent. Timing and mode of delivery is individualized, but the general scheme is to induce labour around the 38th week of pregnancy. It is emphasized that an increased risk of sudden intrauterine death still exists in late diabetic pregnancy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02427274
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    GAD65 autoantibodies in women with gestational or insulin dependent diabetes mellitus diagnosed during pregnancy (1996)
    Springer
    Diabetologia 39 (1996), S. 1329-1333 
    Details
    ISSN: 1432-0428
    Keywords: Keywords GAD65 ; IAA ; ICA ; HLA ; gestational diabetes ; pregnancy.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We have studied the presence of GAD65 autoantibodies in women with insulin-dependent diabetes mellitus (IDDM) (n = 28) or gestational diabetes (GDM) (n = 139) diagnosed during pregnancy and investigated the temporal relationship between these autoantibodies and the subsequent recurrence or development of IDDM. Among the GDM patients, 4.3 % (6 of 139) developed true IDDM during a median follow-up period of 6.3 years (range 4.0–11.0). Of these, 2.2 % (3 of 139) were positive for GAD65 autoantibodies at diagnosis of GDM compared to 0 % (0 of 27) of healthy pregnant women. All 3 GAD65 autoantibody positive GDM patients subsequently developed IDDM after a median of 14 months (range 4–34). GAD65 autoantibodies were present in 50 % (14 of 28) of sera from women with IDDM diagnosed during pregnancy. The non-insulin-requiring remission period was significantly shorter in GAD65 autoantibody positive patients (median 0.5 years [range 0–6.0 years]) than in GAD65 antibody negative patients (median 2.6 years; range 0–9.7 years; p 〈 0.05). The results suggest that screening for GAD65 autoantibodies in women with GDM or IDDM diagnosed during pregnancy may be useful for predicting the clinical course of the disease. [Diabetologia (1996) 39: 1329–1333]
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001250050578
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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