ISSN:
1432-1335
Keywords:
Carcinoma of lung
;
Epidermoidal type
;
HLA antigens
;
Survival time
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary HLA-A and B antigens were determined in a study of 162 patients (93 epidermoid type, 20 adenocarcinoma, 26 small-cell carcinoma and 23 undifferentiated types) with lung cancer. Differences between antigen frequencies in cancer and control populations were studied by χ Y 2 analysis or Fisher's exact test. Survival data were analyzed using Cox's model for censored data. Cancer patients had a decreased frequency of the antigen HLA-B40 (χ Y 2 =14.15,P=0.00018,P c=0.003, relative risk=0.21). Patients with HLA-A10, A 11 and B27 had a shortened mean survival time. Patients with HLA-B12 had a prolonged survival time.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01613006
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