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  • 1
    Electronic Resource
    Electronic Resource
    Central haemodynamics and regional blood flow during halothane-nitrous oxide anaesthesia and controlled ventilation (1983)
    Springer
    Research in experimental medicine 182 (1983), S. 193-201 
    Details
    ISSN: 1433-8580
    Keywords: Rat ; Halothane ; Anaesthesia ; Regional blood flow
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The haemodynamic effects of halothane-N2O/O2 anaesthesia with controlled ventilation were studied in rats, using the microsphere method. Mean arterial blood pressure was significantly reduced but only minor effects on cardiac output (CO), heart rate, and systemic vascular resistance were seen. During anaesthesia, there were significantly increased fractions of CO delivered to brain, lungs, small intestine and liver (hepatic artery), while the fractions to spleen, stomach and carcass were decreased. Fractional distribution and regional blood flow to heart, kidneys, adrenals and preportal area remained unchanged. When anaesthesia was prolonged from 60 to 90 min, no further changes in central or regional haemodynamics were seen. Considering the minor effects on central haemodynamics and the abscense of changes in central and regional haemodynamics at 60 and 90 min, this anaesthesia model should be useful in experimental research.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01851708
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The influence of different levels of PEEP on peripheral tissue perfusion measured by subcutaneous and transcutaneous oxygen tension (1992)
    Springer
    Intensive care medicine 18 (1992), S. 474-478 
    Details
    ISSN: 1432-1238
    Keywords: Subcutaneous oxygens tension ; Transcutaneous oxygen tension ; Tissue perfusion ; PEEP ; Cardiac output ; Oxygen delivery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective To compare subcutaneous (PscO2) and transcutaneous (PtcO2) oxygen tension measurements in relation to hemodynamic variables at different levels of PEEP, and to evaluate the usefulness of these measurements as monitors of peripheral tissue perfusion. Design Prospective trial. Setting Intensive care unit in a university hospital. Patients Seven patients with gastric cancer who where undergoing total gastrectomy. Interventions Silicone catheter was placed in the upper arm and transcutaneous oxygen monitor was placed on the upper part of the chest. A pulmonary artery catheter was placed in the right pulmonary artery. Measurements and results PscO2 and PtcO2 together with hemodynamic variables were measured at different levels of PEEP. Progressive increase of PEEP reduced cardiac index (CI) (p〈0.05) with a concomitant decrease of PscO2 (p〈0.05) and oxygen delivery (DO2) (p〈0.05). Changes in PtcO2 parallelled changes in arterial oxygen tension (PaO2), but no correlation was found between PtcO2, CI and DO2. Conclusion PscO2 is a sensitive indicator of subcutaneous tissue perfusion, which can be used to identify the PEEP level, with optimum peripheral perfusion. PscO2 seems to be a more reliable indicafor of tissue perfusion than PtcO2.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01708584
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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