ISSN:
1432-1238
Keywords:
Hemofiltration
;
Flecainide
;
Atrial fibrillation
;
Pharmacokinetics
;
Renal failure
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Flecainide, a new antiarrhythmic drug, has been shown not no be removed to a significant extent by hemodialysis or peritoneal dialysis, in spite of a high renal clerance. Its systemic and hemofiltrate clearances, measured in a patient under continuous hemofiltration, were 402 and 19.7 ml/min respectively. The clearance ratio of less than 5% makes the contribution of hemofiltration to the elimination of flecainide clinically negligeable.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00717997
Permalink