ISSN:
1432-2277
Keywords:
Kidney transplantation, hepatocyte growth factor
;
Rejection, kidney transplantation, hepatocyte growth factor
;
Hepatocyte growth factor, rejection, kidney transplantation
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Hepatocyte growth factor (HGF), a long sought-after hepatotrophic factor, has recently been shown to act as a renotrophic factor in regeneration of the kidney. We investigated serum HGF levels in 16 renal transplant patients. In patients with acute rejection, the serum HGF level was markedly increased (over 1 ng/ml), and its elevation was accompanied by an increase in serum creatinine and blood urea nitrogen (BUN). In contrast, serum HGF levels were continuously low in patients without rejection. We conclude that serum HGF may become a clinically useful marker for the assessment of acute renal rejection.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00336393
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