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  • 1
    Electronic Resource
    Electronic Resource
    Pregnancy specificβ 1-Glycoprotein (SP1) conversion of SP1β to SP1α by “Acidification”: An artefact (1982)
    Springer
    Archives of gynecology and obstetrics 231 (1982), S. 141-147 
    Details
    ISSN: 1432-0711
    Keywords: Pregnancy proteins ; Pregnancy specific β1-glycoprotein (SP1) ; Heterogeneity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Late pregnancy serum and plasma were examined in rocket immunoelectrophoresis (RIE) and crossed immunoelectrophoresis (XIE) before and after “acid treatment” (pH 2.5, 10 min). The analysis revealed changes in the precipitation morphology in the majority of circulating proteins extending from the albumin to the γ-region. In RIE, the precipitation pattern of SP1 was altered, this change being independent of polyethylene glycol. In addition, XIE analysis of SP1 revealed a change in the precipitation morphology with no change in electrophoretic mobility. The results can be explained by non-specific aggregation and denaturation due to “acid treatment”, and are therefore unlikely to be of any biological or immunochemical importance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02111666
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Outcome of assisted reproduction technology in infertile couples of consanguineous marriage (1996)
    Springer
    Journal of assisted reproduction and genetics 13 (1996), S. 279-281 
    Details
    ISSN: 1573-7330
    Keywords: consanguinity ; infertility ; assisted reproduction ; outcome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Purpose: The outcome of pregnancies resulting from assisted reproduction technology does not seem to differ from the outcome of those arising from spontaneous natural conception. Methods: There is increased risk of chromosomal abnormality in spontaneous natural pregnancies resulting from consanguineous marriage, with consequent higher rates of miscarriage, stillbirth, and congenital abnormalities. Results: This study has shown a trend of an increased miscarriage rate (but not statistically significant) in pregnancies achieved in infertile couples of consanguineous marriages by assisted reproductive technology. Conclusions: Selecting embryos for transfer on the basis of their morphology does not appear to reduce the risk of chromosomal abnormality in these couples.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02070138
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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