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  • 1
    Electronic Resource
    Electronic Resource
    Temporal lobe epilepsy with varying severity: MRI study of 222 patients (1997)
    Springer
    Neuroradiology 39 (1997), S. 788-796 
    Details
    ISSN: 1432-1920
    Keywords: Key words Temporal lobe epilepsy ; Hippocampal sclerosis ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract MRI was performed in 222 consecutive adult patients with temporal lobe epilepsy of varying severity from January 1991 to May 1993. The diagnosis of hippocampal sclerosis was established visually by three independent observers. The accuracy of visual assessment of hippocampal asymmetry was compared with volumetric measurements. Neuropathological correlations were obtained in 63 patients with refractory seizures. Temporal lobe abnormalities were observed in 180 patients (81 %) as follows: hippocampal sclerosis in 122 (55 %); developmental abnormalities in 16 (7.2 %); tumours in 15 (6.8 %); scars in 11 (5 %); cavernous angiomas in 10 (4.5 %); miscellaneous lesions in 6. MRI was normal or showed unrelated changes in 42 patients (19 %). Visual assessment correctly lateralised hippocampal sclerosis in 79 of the 84 patients measured (94 %). Temporal lobectomy confirmed the MRI data (side and aetiology) in all 63 operated patients. Patients with normal MRI had an older age of seizure onset and were more often drug-responsive than patients with hippocampal sclerosis. MRI showed temporal lobe abnormalities in 81 % of epileptic patients with varying severity with good neuropathological correlation. Patients with normal MRI had a less severe form of the disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002340050507
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    MRI evaluation of tuberous sclerosis (1987)
    Springer
    Neuroradiology 29 (1987), S. 437-443 
    Details
    ISSN: 1432-1920
    Keywords: Tuberous sclerosis ; Brain, MRI studies ; Brain, CT studies ; Giant aneurysm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The authors present four cases of tuberous sclerosis examined with MRI. The patho-anatomic aspects are reviewed and analysed with respect to MRI data. MRI appears superior to the CT particularly for imaging of cortical tubers, cystic lesions, and heterotopic clusters; these last two features were never described with MRI before. Here is also presented the second progressive case of giant intracranial aneurysm associated with tuberous sclerosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00341739
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Gadolinium-DTPA enhanced MR imaging in tuberous sclerosis (1990)
    Springer
    Neuroradiology 31 (1990), S. 492-497 
    Details
    ISSN: 1432-1920
    Keywords: Tuberous sclerosis ; Magnetic resonance imaging ; Computed tomography ; Gadolinium-DTPA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Ten patients with clinical tuberous sclerosis were examined with CT and MR imaging, before and after IV contrast in order to determine the role of Gd-DTPA. Gd-DTPA enhancement occured in eleven subependymal nodules which did not enhance on CT after IV contrast. As illustrated by previous CT and pathologic observations and related to the histologic similarity of the subependymal nodules and giant-cell astrocytomas, these hyperintense nodules could represent active lesions with the potential to evolve. Four giant-cell astrocytomas were detected both with CT and Gd-DTPA-enhanced MRI; tumor conspicuity and size assessment were improved by postcontrast MRI in two cases. No cortical tuber or heterotopic cluster enhanced; T2-weighted sequences therefore remain necessary for their detection. If pre and post-Gd-DTPA T1-and T2-weighted imaging is negative, CT is clearly the most sensitive modality in the detection of the small calcified subependymal nodules.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00340129
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    Paper (German National Licenses)
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