ISSN:
1432-0533
Keywords:
Creutzfeldt-Jakob Disease
;
Microdensitometry
;
Histochemistry
;
Lysosome
;
Enzymes
;
Oxidative Enzymes
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary A variety of histochemical reactions were studied in a case of Creutzfeldt-Jakob disease and these were compared with normal brain. Several enzymes were assessed quantitatively using microdensitometric techniques. Neurones showed a loss of both oxidative and lysosomal enzymes. There was a raised activity in adjacent reactive glial cells. Affected cells also showed accumulation of lipofuscin pigment and loss of cytoplasmic RNA and nuclear DNA.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00684430
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