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  • 1
    Electronic Resource
    Electronic Resource
    Lipoprotein uptake by vascular smooth muscle cells of the rat cultured in 5% or 20% oxygen (1983)
    Springer
    Cell & tissue research 233 (1983), S. 453-462 
    Details
    ISSN: 1432-0878
    Keywords: Cell culture ; Lipoprotein ; Hypoxia ; Vascular cells
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Freshly dispersed aortic smooth muscle cells of the rat were grown in either 5% or 20% oxygen. Cells proliferated more rapidly in 5% than in 20% oxygen although at confluency the protein content per cell was 20% less in the 5% than in the 20% oxygen environment. By electron microscopy, cell morphology was the same in both environments. Uptake of low-density and high-density homologous lipoprotein was unaffected by oxygen tension. Other studies, however, showed that induction of receptors for lipoprotein binding behaved variably in the low compared to the high oxygen condition. These differences were not associated with differences in lipid synthesis in the two conditions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00238310
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Growth of aortic vascular smooth muscle cells in lowered oxygen tension (1981)
    Springer
    Cell & tissue research 216 (1981), S. 591-602 
    Details
    ISSN: 1432-0878
    Keywords: Vascular smooth muscle ; Tissue culture ; Hypoxia ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Primary cultures of vascular smooth muscle cells, isolated from rat aorta, were grown under normoxic (20% O2) and mildly hypoxic (5 % O2) conditions. Cells from both conditions were compared for growth characteristics, morphology, protein synthesis, lysosomal enzyme activity, and oxygen consumption. In no case was a consistently significant difference observed. These observations indicate that these cells can adapt or are adapted to mildly hypoxic conditions. Moreover, these results may indicate that the culture of vascular smooth muscle cells in mild hypoxia represents a closer approximation of in vivo growth conditions for these cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00238654
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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