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  • IL-2 receptor  (1)
  • Membrane-bound ATPase  (1)
  • Protonmotive force  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Hydrolysis and synthesis of ATP by membrane-bound ATPase from a motile Streptococcus (1978)
    Springer
    Archives of microbiology 119 (1978), S. 31-36 
    Details
    ISSN: 1432-072X
    Keywords: Motile Streptococcus ; Membrane-bound ATPase ; DCCD ; Valinomycin ; Uncouplers ; Protonmotive force ; ATP synthesis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract ATPase was detected in the membranes of a motile Streptococcus. Maximal enzymic activity was observed at pH 8 and ATP/Mg2+ ratio of 2. Mn2+ and Ca2+ could replace Mg2+ to some extent. Besides ATP, GTP and ITP were substrates. The enzyme was inhibited by N,N′-dicyclohexylcarbodiimide but not by sodium azide, uncouplers or bathophenanthroline. An electrochemical gradient of protons, which was artificially imposed across the membranes of Streptococcus cells by manipulation of either the K+ diffusion potential or the transmembrane pH gradient, led to ATP synthesis. ATP synthesis was abolished by proton conductors, an inhibitor of the ATPase or an increase in the extracellular K+ concentration. A comparison between the phosphate potential and the electrochemical proton gradient showed that the data found are in agreement with a stoichiometry of 2 protons translocated per molecule ATP synthesized.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00407924
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Changes in T-cell subpopulations in mice during prolonged experimental secondary infection withEchinococcus granulosus (1995)
    Springer
    Bioscience reports 15 (1995), S. 201-208 
    Details
    ISSN: 1573-4935
    Keywords: Echinococcus granulosus ; hydatidosis ; flow cytometry ; lymphocytes-T ; splenocytes ; thymocytes ; IL-2 receptor ; CD3-CD4-CD8-CD25
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Balb/c mice were infected intraperitoneally with protoscoleces ofEchinococcus granulosus. After 15 months of infection, and by means of flow cytometry, the expression of T-cell markers CD3, CD4, and CDS on T cells from peripheral blood, spleen, and thymus was analyzed and compared with that of age-matched controls. Infected mice had higher percentages of CD3+, and CD4+ cells in peripheral blood, and higher percentages of CD8+ cells in the spleen, when compared with control mice. CD4+ and CD8+ cells in peripheral blood and CD8+ cells in thymus also showed higher percentages of expression of interleukin-2 receptor. The results infer a role for interleukin-2 in experimental secondary echinococcosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01540454
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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