ZIB

Hits per page

hits 1 - 2 | 2 hits

Sorting

Electronic Resource

Mammosomatotroph adenoma of the pituitary associated with gigantism and hyperprolactinemia. A morphological study including immunoelectron microscopy (1986)

Felix, I. A. ; Horvath, E. ; Kovacs, K. ; [et al.]

Springer

Acta neuropathologica 71 (1986), S. 76-82

add to mindlist on the mindlist

Details

ISSN: 1432-0533

Keywords: Gigantism ; Hyperprolactinemia ; Immunoelectron microscopy ; Mammosomatotroph ; Pituitary adenoma

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary A 29-year old giantess with growth hormone excess and hyperprolactinemia underwent transsphenoidal surgery to remove her pituitary tumor. Electron microscopy revealed a mammosomatotroph adenoma composed of one cell type. Immunoelectron microscopy, using the immunogold technique, demonstrated predominantly growth hormone or prolactin or a varying mixture of both growth hormone and prolactin in the adenoma cells. The presence of growth hormone and prolactin was found not only in the cytoplasm of the same adenoma cells but also in the same secretory granules. In the nontumorous adenohypophysis, somatotrophs and lactotrophs showed ultrastructural signs of hyperactivity. This finding is in contrast with the presence of suppressed somatotrophs and lactotrophs seen in nontumorous portions of adult pituitaries harboring growth hormone or prolactin-secreting adenomas. Our morphological study reinforces the view that growth hormone-producing pituitary tumors, originating in childhood, are different from those of the adult gland.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00687965

Permalink

Library	Location	Call Number	Volume/Issue/Year	Availability

Others were also interested in ...

Paper (German National Licenses)

Fulltext

Electronic Resource

Hydroxyl radical measurements in a photochemical reactor by laser-induced fluorescence (1976)

Wu, C. H. ; Wang, Charles C. ; Japar, S. M. ; [et al.]

New York, NY : Wiley-Blackwell

International Journal of Chemical Kinetics 8 (1976), S. 765-776

add to mindlist on the mindlist

Details

ISSN: 0538-8066

Keywords: Chemistry ; Physical Chemistry

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology

Notes: Measurements of hydroxyl radical (HO) concentrations in ambient air by the technique of laser-induced fluorescence have been recently reported. The present study was undertaken to provide an independent test of the validity of those measurements. A photochemical reactor was used to provide a source of HO, and the concentration of HO in the reactor was determined by the laser-induced fluorescence technique. The HO concentration was also deduced from measured hydrocarbon decay rates in the reactor. There was agreement between the HO concentrations obtained by these two different methods, thus providing further validation of the fluorescence method. Some studies of HO fluorescence efficiency as well as of possible interferences with the fluorescence measurements are reported.

Additional Material: 4 Ill.