ISSN:
1432-2307
Keywords:
Hepatocellular carcinoma
;
Immunohistochemistry
;
Prolonged survival
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Two cases of well-differentiated hepatocellular carcinoma (HCC) with focal biliary differentiation are presented. The distinct histological features of these neoplasms and the unusually protracted clinical course of 8 and 10 years distinguish them from previously described pathological categories of primary hepatic tumors. Electron microscopic and immunohistochemical findings support a dual hepatic and bile duct differentiation of the tumor cells. If additional examples of this tumor are found to be associated with a similarly prolonged symptom-free survival, the distinction of this entity from traditional, rapidly fatal HCC becomes important. Less aggressive therapeutic options may be entertained.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01606507
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