ISSN:
1572-8854
Keywords:
Folk Medicine
;
Limonoid
;
Antimalarial
;
Immunomodulator
Source:
Springer Online Journal Archives 1860-2000
Topics:
Geosciences
,
Physics
Notes:
Abstract The crystal and molecular structure of the natural product C29H38O9, an extract from a Cameroonian plant, has been determined by direct methods. Crystals are orthorhombic, P212121,a=24.571(4),b=16.398(3),c=13.778(4) Å,Z-8,D c=1.270 mg/m3. The final R-factor for 2892 reflections withI〉2σ(I) is 0.0531. The two molecules forming the asymmetric unit have very similar molecular geometry. each molecule comprising a nucleus of six fused rings B to G: where B=pyranyl, C=pyranyl, D=furanyl, E=cyclohexene, F=pyranyl, G=cyclohexyl. Ring B also has a furanyl side-group (ring A). The ring conformations in both molecules are: A (1/2-chair/envelope); B(envelope); C(envelope); D(1/2-chair); E(1/2-chair); F(envelope); G(chair). In the cyclohexene ring E the substitution pattern is 2-hydroxy 3-methyl 5-dimethyl. The two molecules in the asymmetric unit are linked by two OH...O hydrogen bonds to form the crystal structure.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01668240
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