ISSN:
1432-1440
Keywords:
Immunosuppressive acidic protein
;
Pregnancy
;
Ovarian Cancer
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Serum levels of immunosuppressive acidic protein (IAP) were determined in 48 healthy controls (age: $$\bar x = 37.8 \pm 13.8$$ years) and 72 pregnant women (age: $$\bar x = 27.05 \pm 5.5$$ ). The mean value of IAP in pregnant women (345.3±94.4 µg/ml) was significantly lower than that of the healthy control group (P〈0.0001; 452.0±95.0 µg/ml). Correlated to the clinical status were 207 IAP serum values of 63 patients with ovarian cancer (age: $$\bar x = 56.9 \pm 11.1$$ ). The mean value of patients with tumor progression ( $$\bar x = 799.3 \pm 292.2\,\mu g/ml$$ ) was significantly increased compared to those of patients in remission ( $$\bar x = 511.0 \pm 111.9\,\mu g/ml$$ ) and the control group ( $$\bar x = 463 \pm 146.8\,\mu g/ml$$ ;P〈0.0001). However, no significant difference of the IAP levels was found between the group in remission and the healthy controls. With a threshold value of 640 µg/ml we found right-negative values in 88.7% and right-positive values in 65.1% during the follow-up of patients with ovarian cancer.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01734839
Permalink
