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  • 1
    Electronic Resource
    Electronic Resource
    The spectrum of gastrointestinal radiology in AIDS (1991)
    Springer
    European radiology 1 (1991), S. 33-45 
    Details
    ISSN: 1432-1084
    Keywords: AIDS ; Gastrointestinal manifestations ; Opportunistic infections ; Kaposi's sarcoma ; Non-Hodgkin lymphoma ; B-cell lymphoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Twohundred and twenty-five adult patients with AIDS were seen at the Academic Medical Center over a 5-year period. Of these patients, 70% were found to have gastrointestinal disease: 32% oropharyngeal candidiasis: 12,5% cytomegalovirus infection, mostly in rectum or colon (5.3%), and 8% mycobacterium. Kaposi's sarcoma, which has been reported in 27% of the cases in literature, was present in 29%, of our patients. We had a rather ow incidence of non-Hodgkin lymphoma of the gastrointestinal tract (1,3%). With double-contrast barium studies of the GI tract early superficial mucosal changes can be detected. Endoscopy, especially in Kaposi's sarcoma, may be complementary.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00540101
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Inflammatory bowel disease and the genes for the natural resistance-associated macrophage protein-1 and the interferon-Á receptor 1 (1999)
    Springer
    International journal of colorectal disease 14 (1999), S. 13-17 
    Details
    ISSN: 1432-1262
    Keywords: Key words Crohn's disease ; Inflammatory bowel disease ; Interferon-γ receptor1 ; Natural resistance associated macrophage protein-1 ; Polymorphisms ; Ulcerative colitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The genes for the interferon-γ receptor1 and the natural resistance-associated macrophage protein1 (NRAMP1) control the immune response to intracellular microbial pathogens. Such pathogens, in particular Mycobacterium paratuberculosis, have been implicated in the pathogenesis of Crohn's disease. We studied markers in the genes for NRAMP1 and two mutations in the interferon-γ receptor in relation to inflammatory bowel disease (IBD) in the following groups: 270 healthy individuals, 74 patients with Crohn's disease, 72 patients with ulcerative colitis, and 40 patients with primary sclerosing cholangitis. We studied the allele frequencies of two restriction fragment length polymorphisms in the gene for NRAMP1 and the prevalence of two mutations in the interferon-γ receptor1 gene. The markers in the NRAMP1 gene were not associated with inflammatory bowel disease. Also, the mutations in the interferon-γ receptor1 were not found in the 186 IBD patients. Genetic markers in NRAMP1 are thus not associated with IBD. Therefore this gene is not likely to play a role in the pathogenesis of IBD. The mutation in the interferon-γ receptor was not found in our IBD patients group.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003840050177
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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