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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European archives of oto-rhino-laryngology and head & neck 230 (1981), S. 177-180 
    ISSN: 1434-4726
    Keywords: Perilymphelektrolyte ; Glycerolapplikation ; Innenohrflüssigkeiten ; Perilymph electrolytes ; Glycerol administration ; Inner ear fluids
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Serum, cerebrospinal fluid (CSF), scala vestibuli perilymph, and scala tympani perilymph were collected from 85 normal guinea pigs both before and after i.v. administration of glycerol (1 ml/kg), and the sodium and potassium concentrations were assessed using a microflame photometer. Marked increases in sodium concentrations were observed in scala tympani perilymph and CSF, while there was a slight decrease in the serum and there was no significant change in scala vestibuli perilymph. These increases in sodium concentrations are considered to occur in the dehydration process in the body fluids mentioned above. On the other hand, increase in the potassium concentrations was found only in scala vestibuli perilymph and thus cannot be explained by simple dehydration process. This potassium elevation in scala vestibuli perilymph should be understood by further experiment on endolymph. It became evident that scala vestibuli perilymph differs from scala tympani perilymph and CSF in the dynamics of electrolytes after glycerol administration. In this regard, the nature of the scala vestibuli as fluid space should be studied in future. The above findings obtained in the present study may imply the significance in elucidating the glycerol effect on hearing of endolymphatic hydrops case.
    Notes: Zusammenfassung Blutserum, Liquor cerebrospinalis und Perilymphe von Scala vestibuli und Scala tympani wurden von 85 normalen Meerschweinchen vor und nach i.v. Glycerolapplikation entnommen und die Na- und K-Konzentration bestimmt. Dabei wurde nach Glycerolgabe ein deutlicher Anstieg der Na-Konzentration in der Perilymphe der Scala tympani und im Liquor festgestellt, während die Perilymphe der Scala vestibuli keine Veränderungen zeigte. Die Zunahme der Na-Konzentration wird auf die Dehydration durch das Glycerol zurückgeführt, wobei die unterschiedliche Reaktion beider Perilymphen noch weiterer Untersuchungen bedarf. Die erhobenen Befunde könnten zur Aufklärung der Glycerolwirkung auf das Hören beim endolymphatischen Hydrops von Bedeutung sein.
    Type of Medium: Electronic Resource
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