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  • Inorganic phosphate reabsorption  (1)
  • TmPAH  (1)
  • 1
    ISSN: 1432-2013
    Keywords: Renal denervation ; Sodium excretion ; Para-aminohippuric acid secretion ; TmPAH
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Renal excretion of para-aminohippuric acid (PAH) was studied during PAH loading on unilaterally splanchnicotomized (“denervated”) anaesthetized dogs. Urine flow, sodium excretion of denervated kidneys were significantly increased. Below a plasma concentration of 20 mg% there were no differences between intact and denervated kidneys in urinary excretion and in calculated tubular transport of PAH. However, maximum secretion rate on the splanchnicotomized side was significantly decreased (innervated: 34.8, denervated: 25.2 mg/100 ml GFR, respectively). Although both Na reabsorption and PAH secretion are impaired by denervation, the exact mechanism of action of renal sympathectomy is not elucidated as yet.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 367 (1977), S. 283-286 
    ISSN: 1432-2013
    Keywords: Renal denervation ; Sodium excretion ; Inorganic phosphate reabsorption
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effects of acute i.v. inorganic phosphate (P i ) loading were studied on nembutalized mongrel dogs previously subjected to unilateral splanchnicotomy (“renal denervation”). GFR (51Cr-EDTA) was not different on the intact and the denervated side, while urine output (V), sodium excretion (UNaV), and urinary excretion (UP i V) of inorganic phosphate of denervated kidneys were significantly increased at any plasma P i level. Thus, tubular reabsorption of P i in denervated kidneys was considerably depressed. Tubular transport rates of Na and P i —as expressed in per cent of the filtered load—were positively correlated in both intact and denervated organs. Besides an impairment in tubular transport of Na a depression in the reabsorption of inorganic phosphate is brought about by renal denervation. A common mechanism of action for both Na and P i can be supposed.
    Type of Medium: Electronic Resource
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