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  • Iotrolan  (1)
  • Low-osmolar contrast media  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Iotrolan in cerebral angiography: a Japanese phase III multicenter comparative study with iopamidol (1995)
    Springer
    European radiology 5 (1995), S. S39 
    Details
    ISSN: 1432-1084
    Keywords: Cerebral angiography ; Iotrolan ; Iopamidol
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The clinical benefit of iotrolan, a non-ionic dimeric contrast agent, was compared with the commonly used non-ionic contrast agent iopamidol, in a multicenter study in cerebral angiography. Iotrolan provided a diagnostic angiographic effect with a reduced rate of adverse events when compared with iopamidol. Heat sensations at the site of iotrol an injection were apparently milder than with iopamidol, and no effects on hematology, blood biochemistry or urinalysis were observed. The clinical benefit of iotrolan, assessed after consideration of imaging efficacy and overall safety, was good.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02343259
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Diagnostic efficacy and safety of two low-osmolar contrast media in cerebral angiography (1994)
    Springer
    European radiology 4 (1994), S. 185-189 
    Details
    ISSN: 1432-1084
    Keywords: Cerebral angiography ; Contrast agents ; Ionicity, osmolality ; Low-osmolar contrast media
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A comparative randomised open study was carried out in 120 patients uncle undergoing cerebral angiography, to compare two low-osmolar contrast media (LOCM). All the patients participated voluntarily in the trial. Half the patients (n = 60) received sodium and meglumine ioxaglate (Hexabrix 320) and the other half (n = 60) iohexol (Omnipaque 300). Contrast agent efficacy was evaluated at the different cerebral levels explored. Adverse reactions were recorded immediately and 24 h post-administration. Diagnostic quality was considered excellent in 95% of cases with Omnipaque and in 97% of cases with Hexabrix. Image quality was excellent in 95%, of cases with Omnipaque and in 100 % of cases with Hexabrix. In terms of both efficacy and safety, no significant difference was observed between the agents. Thus, low osmolality would appear to be the essential factor in this indication as far as safety is concerned. No significant difference in safety was noted between the ionic LOCM Hexabrix and the non-ionic LOCM Omnipaque.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00606445
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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