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Morphine analgesia in grouped and isolated rats (1975)

Adler, M. W. ; Mauron, C. ; Samanin, R. ; [et al.]

Springer

Psychopharmacology 41 (1975), S. 11-14

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ISSN: 1432-2072

Keywords: Morphine Analgesia ; Isolation in Rats ; Muricidal Behavior

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract The effects of long-term isolation of young adult male rats on the analgesic effects of morphine were investigated. Isolated rats developed altered patterns of behavior, including muricidal behavior in some animals. Analgesic activity of morphine was assessed with both the tail compression and the hot plate methods. The results indicate that chronically isolated rats, whether developing muricidal behavior or not, show no alteration in either pain thresholds or in their response to morphine-induced analgesia.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00421298

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