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  • Key words: Bafilomycin A1—Phagocytosis—Reactive oxygen species—Cytosolic pH.  (1)
  • Video Bildmisch-verfahren, Schädelidentifizierung  (1)
  • Video-Superimpositionstechnik, Kraniometrie  (1)
  • 1
    ISSN: 1437-1596
    Keywords: Skull identification via video superimposition technique ; Video superimposition technique ; Craniometry ; Schädelidentifizierung durch Video-Superimpositionstechnik ; Video-Superimpositionstechnik, Kraniometrie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Die Identifizierung eines unbekannten Schädels durch Vergleich der Fotos von vermißten Personen mit Hilfe der Video-Bildmischtechnik stützt sich auf die Tatsache, daß der menschliche Schädel wie kein anderer Teil des menschlichen Skelettes unverwechselbare individuelle Merkmale zeigt. Um eine Quantifizierung dieser Individualität menschlicher Schädel zu erhalten, wurde die Wahrscheinlichkeitsverteilung kraniometrischer Daten untersucht. Erste Ergebnisse der Berechnungen, die sich auf die Raum-Koordinaten einiger wichtiger kraniometrischer Bezugspunkte von 52 europäischen Schädeln stützen, haben Individualitätswerte ergeben, die in ihrer Wertigkeit mit Fingerabdrücken verglichen werden können. Unter bestimmten Voraussetzungen kann die Video-Bildmischtechnik bei der Untersuchung unbekannter Schädel den Identitätsbeweis liefern, vorausgesetzt, daß diese Methode mit größter Genauigkeit und Sorgfalt angewendet wird.
    Notes: Summary The possibility of using the video superimposition technique for the identification of a skull by comparing it with photographs of missing persons is based on the fact that the human skull, unlike any other part of the human skeleton, shows unmistakable individual characteristics. In order to obtain a quantification, the individuality of human skulls is defined in terms of craniometric data and their probability distribution. First calculations based on the coordinates of some important encephalometric points of 52 European skulls suggest that there are individual aspects comparable to those of fingerprints. Under certain conditions, the video superimposition technique can establish very strong evidence for the identity of an unknown skull, provided that it is applied correctly and carefully.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1750
    Keywords: Key words: Bafilomycin A1—Phagocytosis—Reactive oxygen species—Cytosolic pH.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Bafilomycin A1, a selective inhibitor of V-type H+-translocating ATPase (V-ATPase), may be a useful adjunct in cancer chemotherapy (Altan et al. [1998] J Exp Med 187:1583–1598). Therapeutic uses of the enzyme inhibitor need to consider the agent's potential effects on normal (nontumor) cells. This study determined the effects of bafilomycin A1 on resident alveolar macrophages (mφ). Treatment of alveolar mφ with bafilomycin A1 (10 μM, 1 h) caused a significant decrement in cytosolic pH. This was accompanied by marked alteration of mφ bactericidal capabilities. The enzyme inhibitor caused a marginal reduction in the phagocytosis of opsonized Staphylococcus aureus and significantly suppressed intracellular killing of the phagocytosed bacteria. In keeping with the effects on intracellular killing, bafilomycin A1 significantly reduced the production of reactive oxygen species (ROS). On the other hand, cell spreading was enhanced significantly by bafilomycin A1. Comparable changes in ROS generation and mφ spreading were produced by altering cytosolic pH through changes in extracellular pH (pHo) in the absence of bafilomycin A1. These findings suggest that the agent's effects on ROS production and mφ spreading were related to the accompanying changes in cytosolic pH. The enzyme inhibitor also altered mφ morphology, leading to the shortening of microvilli and focal loss of surface ruffles. These morphologic effects differed from those produced by altering cytosolic pH by changes in pHo. The results demonstrate that V-ATPase activity is an important determinant of mφ functioning and structure. Therapeutic use of V-ATPase inhibitors might be expected to compromise the bactericidal activity of alveolar mφ.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    International journal of legal medicine 80 (1977), S. 189-190 
    ISSN: 1437-1596
    Keywords: Schädelidentifizierung, Video-Bildmischverfahren ; Video Bildmisch-verfahren, Schädelidentifizierung
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Die Schädelidentifizierung nach dem Verfahren der elektronischen Bildmischung konnte mit Hilfe eines Video-Trickmischers über die reine Superprojektionsmethode hinaus zu einem Trickbild-Differenz-Verfahren weiter-entwickelt werden. Die Anwendung dieser Techniken in Kombination ist wegen der dadurch gegebenen verbesserten Kontrollmöglichkeit der Kongruenz des Superprojektionsmisch-bildes sehr zu empfehlen.
    Notes: Summary Skull identification by electronic photo-composition can, with the help of a video-animation compositor, be further developed beyond the pure superprojection technique into an animated picture-difference image. The employment of this combined technique is to be recommended on account of the improved possibilities of control to be realized in the congruity of the superprojection composite picture.
    Type of Medium: Electronic Resource
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