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  • Key words: Positron emission tomography  (1)
  • stator system  (1)
  • 1
    Electronic Resource
    Electronic Resource
    The double resonances of magnetism and solid coupling of hydroelectric-generator stator system (2000)
    Springer
    Applied mathematics and mechanics 21 (2000), S. 1187-1196 
    Details
    ISSN: 1573-2754
    Keywords: hydroelectric-generator ; stator system ; method of the multiple scales ; magnetism and solid coupling ; double resonances ; 0321 ; TM312
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Mathematics , Physics
    Notes: Abstract A double-shell model of hydroelectric-generator stator system was established. Applying the theory of mechano-electric analytical dynamics theory, the nonlinear vibration equation of magnetism and solid coupling of hydroelectric-generator stator system, under steadily balanced three-phases operating condition, was obtained. According to the method of multiple scales for nonlinear oscillations, the double resonances of magnetism and solid coupling of hydroelectric-generator stator system were investigated. It is pointed out that the system has abundant dynamics phenomenon including the attendant jumps and coexistence of multiple stable motions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02458997
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  • 2
    Electronic Resource
    Electronic Resource
    The time course of metabolites in human plasma after 6-[18F]fluoro-l-m-tyrosine administration (1999)
    Springer
    European journal of nuclear medicine 26 (1999), S. 1407-1412 
    Details
    ISSN: 1619-7089
    Keywords: Key words: Positron emission tomography ; 6-[18F]- fluoro-l-m-tyrosine ; Plasma metabolites
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. For the investigation of intracerebral dopamine metabolism, 6-[18F]fluoro-l-m-tyrosine (FmT) has been proposed as an alternative tracer that, unlike 6-[18F]fluoro-l-dopa, is not subjected to O-methylation. We have studied the time course of FmT and its labelled metabolites in plasma after intravenous injection into humans, employing a method that we have developed and validated to analyze labelled metabolites of FmT in plasma. The study population comprised 38 subjects, 14 of whom were taking an aromatic amino acid decarboxylase inhibitor (carbidopa), and obtained arterialized venous blood samples at various times after an intravenous injection of between 185 and 370 MBq of FmT. The major metabolite of FmT present in plasma was 6-[18F]fluoro-3-hydroxyphenylacetic acid. The time course of the fraction of radioactivity in plasma attributable to FmT was fitted well by the decay of two exponential functions. The fast component of the decay accounted for 40%–50% of the radioactivity and had a half-life of about 5 min. The slow component of the decay had a half-life of about 6 h in the subjects not taking carbidopa and 20 h in the patients taking carbidopa. When the total available FmT was calculated for each individual subject and expressed as a proportion of total radioactivity, this quantity did not differ significantly from that determined from the corresponding population mean. There was significantly more (15% on average) FmT available over the course of the 2-h experiment in the group pretreated with carbidopa. Our results demonstrate that the major metabolite in plasma after an intravenous injection of FmT is 6-[18F]fluoro-3-hydroxyphenylacetic acid. The clearance of FmT from plasma compares well with the clearance of intravenously administered levodopa. Carbidopa increases significantly the availability of FmT in plasma. These results verify, in a large number of human subjects, earlier analyses of FmT metabolism in other species. We validate a population-derived approach that can adequately describe the time course of FmT in plasma, alleviating the need for metabolite analysis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002590050472
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    Paper (German National Licenses)
    Fulltext
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