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  • Key words: Rhenium-188 diethylene triamine penta-acetic acid – Dosimetry – MIRD – Endovascular brachytherapy – Prevention of restenosis  (1)
  • aging temperature effect  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Dosimetry of rhenium-188 diethylene triamine penta-acetic acid for endovascular intra-balloon brachytherapy after coronary angioplasty (2000)
    Springer
    European journal of nuclear medicine 27 (2000), S. 76-82 
    Details
    ISSN: 1619-7089
    Keywords: Key words: Rhenium-188 diethylene triamine penta-acetic acid – Dosimetry – MIRD – Endovascular brachytherapy – Prevention of restenosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. To examine the possibility of using rhenium-188 diethylene triamine penta-acetic acid (DTPA) for endovascular intra-balloon brachytherapy after angioplasty, dose distribution around the balloon was calculated and validated by film dosimetry. Medical internal radiation dosimetry (MIRD) was calculated assuming that the balloon had ruptured and that the contents had been released into the systemic circulation. 188Re-perrhenate eluate from the 188W/188Re generator was concentrated using an ion column and used to label DTPA. The dose distibution around the angioplasty balloon (20 mm length, 3 mm diameter cylinder) was estimated by Monte Carlo simulation using the EGS4 code. The time required for 17.6 Gy to be absorbed at 1 mm from the balloon’s surface following application of 3700 MBq/ml of 188Re was found to be 278 s. Fifty percent of the energy was deposited in the first millimetre of the vessel wall from the balloon’s surface. The calculated radiation absorbed dose agreed with that measured by film dosimetry, which was performed using a water phantom, with errors ranging from 9.4% to 17%. Upon balloon rupture the total amount of 188Re-DTPA was presumed to enter the systemic circulation. The resulting radiation absorbed dose was calculated using the MIRDOSE3 program and residence times obtained from dogs and amounted to 0.0056 mGy/MBq to the whole body and 4.56 mGy/MBq to the urinary bladder. The absorbed dose of 188Re-DTPA to the whole body was one-tenth of that of 188Re-perrhenate. A window-based program was developed to calculate the exposure time and the radiation dose absorbed as a function of the 188Re concentration and the arbitrary distance from the balloon to the surrounding tissues. We conclude that 188Re-DTPA is easy to prepare, safe to use and suitable for intra-balloon brachytherapy after coronary angioplasty.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00006667
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  • 2
    Electronic Resource
    Electronic Resource
    Synthesis of zeolite rho: Aging temperature effect (1996)
    Springer
    Journal of porous materials 3 (1996), S. 151-155 
    Details
    ISSN: 1573-4854
    Keywords: zeolite rho ; aging temperature effect ; crystallization kinetics ; crystal size
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract This paper focuses on deciphering the gel aging temperature effect on the crystallization of zeolite rho(RHO). Increased gel aging temperature (from room temperature to 55°C and no aging) caused an increase in induction periods and decreased the crystallization rate during the synthesis of RHO. Other crystalline phases such as chabazite were formed along with increasing aging temperature. The largest crystal size of RHO increased proportionally to aging temperatures up to about 9 μm. These results suggest that aging temperature greatly affected the crystallization, the crystal sizes, the purity and the formed crystalline phases during the synthesis of zeolite rho. This study suggests that most of RHO nuclei are formed during gel aging and their formation is depressed by the increased aging temperatures.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01134026
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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