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  • Key words Analytical quality control  (1)
  • ethinylestradiol  (1)
  • 1
    Electronic Resource
    Electronic Resource
    The UK National Marine Analytical Quality Control Scheme (1997)
    Springer
    Accreditation and quality assurance 2 (1997), S. 294-300 
    Details
    ISSN: 1432-0517
    Keywords: Key words Analytical quality control ; Marine monitoring ; Accuracy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract  The approach to analytical quality control adopted for the UK National Marine Analytical Quality Control Scheme is described. The Scheme began in 1991 and is in its fifth year of operation. The aim of the programme of work is to ensure adequate control over the accuracy of analysis, such that the aims of the UK National Marine Monitoring Plan are satisfied. The results of interlaboratory tests for the determination of nutrients in water samples and metals, organic compounds in waters, sediments and biological samples are summarised.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007690050151
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Effect of chronic oral contraceptive steroids on theophylline disposition (1982)
    Springer
    European journal of clinical pharmacology 23 (1982), S. 129-134 
    Details
    ISSN: 1432-1041
    Keywords: theophylline ; ethinylestradiol ; oral contraceptives ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The effect of chronic oral contraceptive (OC) usage on the disposition of theophylline was examined. Aminophylline solution (4 mg/kg) was given orally to 8 healthy female non-OC users and to 8 healthy women who were chronic (〉6 months) OC users. The OC user group had a significantly lower total plasma clearance of theophylline than women not using OC (35.1±5.6 vs. 53.1±14.5 ml/h/kg). The t1/2 was also significantly prolonged in the OC group (9.79±1.43 vs. 7.34±1.75 h) while the volume of distribution was similar between the 2 groups. The serum ethinylestradiol (EE) concentrations after oral OC administration were measured simultaneously. The apparent clearance of EE was about 30% lower in the OC users. A significant positive correlation was found between the apparent clearance of EE and the plasma clearance of theophylline. The effects of OC are predominantly due to chronic use with decreased elimination of both theophylline and EE.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00545966
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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