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  • 1
    Electronic Resource
    Electronic Resource
    Blood pressure and plasma noradrenaline during single high-dose beta adrenoceptor blockade (1979)
    Springer
    European journal of clinical pharmacology 15 (1979), S. 375-379 
    Details
    ISSN: 1432-1041
    Keywords: propranolol ; atenolol ; plasma noradrenaline ; sympathetic activity ; blood pressure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The acute effects upon blood pressure and sympathetic outflow of two beta adrenoceptor blocking drugs, propranolol and atenolol, are described in five healthy normotensive subjects. Supine blood pressure, heart rate, plasma noradrenaline, and urinary catecholamine excretion were measured before and at intervals for 24 h after a single oral dose of either propranolol 200 mg, atenolol 100 mg, or placebo. Propranolol caused a fall in blood pressure and heart rate of 17.2/14.1 mm Hg and 20.4 beats/min respectively two hours after dose. Atenolol caused a fall in blood pressure of 11.4/18.6 mm Hg withih 7 h of the dose, and a fall in heart rate of 13.8 beats/min after 2 h. The reduction in blood pressure after single high dose beta adrenoceptor blockade is established. The synchronous reduction in blood pressure and heart rate after propranolol was not associated with an increase in peripheral sympathetic activity as assessed by the biochemical indices. It is conceivable that the reduction in blood pressure during beta adrenoceptor blockade may be due in part to inappropriately low sympathetic activity but this cannot be the main mechanism of pressure reduction.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00561734
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  • 2
    Electronic Resource
    Electronic Resource
    Outpatient haemorrhoidectomy in a colorectal surgical unit (1999)
    Springer
    Techniques in coloproctology 3 (1999), S. 75-78 
    Details
    ISSN: 1128-045X
    Keywords: Key words Ambulatory surgery ; Haemorrhoids ; Postoperative complications
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract: The number of patients who undergo ambulatory surgery for haemorrhoids has been increasing over the past few years. The aim of present study was to evaluate our experience with ambulatory treatment of haemorrhoids in a dedicated colorectal surgical unit from January 1995 to April 1997. We performed 225 ambulatory haemorrhoidectomies in this period. Mean age of the patients was 49.5 years, 52% of the patients were male, and 48% female. Thirty-two percent of our patients were classified as ASA level II or III. The most frequent procedure was the threequadrant haemorrhoidectomy (87% of patients). Only 20 patients (8.9%) presented with postoperative complications, of these, only five (2.2%) were considered major and required hospital admission. The mean time until the first postoperative visit was 8.2 days, and to the final visit 37.2 days. The mean number of postoperative visits was 2. Patients with complications had a longer postoperative follow-up. Patient satisfaction was high. We thus conclude that outpatient haemorrhoidectomy is safe and cost effective.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s101510050019
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    Paper (German National Licenses)
    Fulltext
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