ISSN:
1590-3478
Keywords:
Cerebral ischemia
;
livedo reticularis
;
Sneddon syndrome
;
coagulation defect
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Description / Table of Contents:
Sommario L'associazione di lesioni cerebrovascolari ischemiche e livedo reticularis è conosciuta come sindrome di Sneddon. La sua eziopatogenesi non è ancora stata chiarita. Noi descriviamo un caso in cui sono stati documentati un aumento dell'attività del fattore VII della coagulazione ed una carenza della forma libera della proteina S.
Notes:
Abstract The association of ischemic cerebrovascular lesions with livedo reticularis is known as Sneddon syndrome. It affects young subjects, primarily women, and its neurological manifestations are TIAs, ischemic stroke, progressive dementia and epileptic seizures. Its etiopathogenesis has still to be clarified. Some authors have associated it with an antiphospholipid antibody syndrome. Recently it has been assumed that a defect in blood coagulation may be involved in its pathogenesis. Here we report a case in which both an increase in coagulation factor VII activity and a deficiency in free protein S were documented.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02233406
Permalink
