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Gastritis cystica polyposa associated with a gastric stump carcinoma, with special reference to cell kinetics and p53 gene aberrations (2000)

Ochiai, Masahiro ; Matsubara, Toshiki ; Zhi, Li Zhu ; [et al.]

Springer

Gastric cancer 3 (2000), S. 165-170

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ISSN: 1436-3305

Keywords: Key words Gastritis cystica polyposa ; Ki-67 LI ; p53 Gene mutation ; p53 Gene deletion

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: We report a case of gastritis cystica polyposa (GCP) that developed in association with a small stump carcinoma. The patient had had distal gastrectomy for peptic ulcer 33 years prior to the present illness. Total gastrectomy was carried out for the stump carcinoma of the remnant stomach, followed by Roux-en-Y anastomosis. Histological examination revealed that the cancer was associated with a GCP lesion in its neighborhood. The resected stomach was subjected to a cell kinetics study and p53 gene analysis, as GCPs are thought to have a high potential for carcinogenesis. The GCP mucosae, as well cancer tissues and remnant mucosae obtained from the same specimens, were investigated and compared. We found that cell kinetics, as measured by a Ki-67 labeling index count, was more accelerated in the GCP than in the remnant mucosa, and that p53 gene aberrations, including both mutations and deletions, took place in the GCP lesion. As the p53 gene is considered to be recessive, in principle, its tumor suppressive activity is lost only when gene aberration, either mutation or deletion, occurs concurrently or successively in both alleles. It was of interest to us that a benign lesion such as GCP had, in this instance, already developed both gene aberrations, strongly suggesting a precancerous nature for this disease.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/PL00011713

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Effect of solvent on anthraquinone-sensitized photopolymerization of methyl methacrylate (1982)

Li, Zhu-Ten ; Kubota, Hitoshi ; Ogiwara, Yoshitaka

New York, NY [u.a.] : Wiley-Blackwell

Journal of Applied Polymer Science 27 (1982), S. 1465-1470

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ISSN: 0021-8995

Keywords: Chemistry ; Polymer and Materials Science

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics

Notes: Photopolymerization of methyl methacrylate was carried out in the system containing anthraquinone (AQ) sensitizer and solvent under nitrogen at 30°C. Hydrocarbons, alcohols, and mixtures of both, for example, cyclohexane and isopropanol, were used as solvents. The maimum yield of polymerization was observed at a certain concentration of alcohol in hydrocarbon, a phenomenon which is discussed from measurements of polymer molecular weight and the UV spectrum of irradiated AQ.

Additional Material: 4 Ill.