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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 372 (1987), S. 145-148 
    ISSN: 1435-2451
    Keywords: Esophageal cancer ; Perioperative chemotherapy ; Oesophaguscarcinom ; Perioperative Chemotherapie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Für die Mehrzahl der Patienten mit Oesophaguscarcinom sind lokale Tumorinfiltrationen und/oder Fernmetastasen bei der Diagnosestellung für die ungünstige Prognose verantwortlich zu machen. Zu deren Verbesserung werden zusätzliche Therapiemodalitäten - Chemotherapie allein oder in Kombination mit simultaner Strahlentherapie — perioperativ eingesetzt. Trotz einer möglichen Steigerung der Resektionsrate fehlen bisher überzeugende Ergebnisse, die angesichts der gesteigerten Toxizität einen Einsatz dieser multimodalen Therapiestrategien ausserhalb von kontrollierten Studien erlauben.
    Notes: Summary In the majority of patients with esophageal cancer local tumor infiltration and/or distant metastases are responsible for the poor prognosis. Therefore to improve life expectancy additional modalities - chemotherapy alone or in combination with simultaneous radiation - have been introduced perioperatively. In spite of a possible increase of resectability convincing data are lacking which could argue for an uncontrolled introduction of the neoadjuvant approach outside investigational studies.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1437-9813
    Keywords: Key words Hodgkin's disease ; Recurrent mediastinal mass ; Gallium-67 SPECT ; Thymic rebound ; Chemoradiotherapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The case of an 11-year-old girl with mediastinal stage III B-E Hodgkin's disease is described. She achieved complete remission with combined chemoradiotherapy according to the Swiss Pediatric Oncology Group-HD Protocol 1985. Six months after all therapy was stopped, a slowly growing retrosternal mass was detected. Computed tomography (CT) and gallium-67 single-photon emission CT (SPECT) could not elucidate the true origin of the tumor, nor did ultrasound-guided transthoracic fine-needle puncture. Open biopsy with histologic examination of the lesion has successfully identified the mass as thymic hyperplasia, a rebound immunologic reaction after chemoradiotherapy that mimicked tumor regrowth.
    Type of Medium: Electronic Resource
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