ISSN:
1439-6327
Schlagwort(e):
Key words Pulse wave velocity
;
Peripheral vascular disease
;
Hypertension
;
Hyperlipidaemia
;
Arterial stiffness
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Medizin
Notizen:
Abstract Non-invasive measurement of arterial pulse wave velocity (PWV) is used to diagnose peripheral vascular disease. We examined the relationship between PWV and risk factors related to peripheral vascular disease [body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure (DBP), serum total cholesterol (TC), high-density lipoprotein-cholesterol (HDL-C), atherogenic index (AI) and blood glucose (GLU)] in 45 healthy male volunteers, aged 25–85 years. The correlation coefficient of PWV with age was r=0.46, and the correlation coefficients of PWV with DBP, AI and GLU were r=0.71, 0.56, and 0.22, respectively (P 〈 0.05). Multiple linear regression analysis revealed that 67% of the variance in PWV could be accounted for by these three variables. The relative contributions of DBP, AI and GLU to PWV were 66%, 26% and 8%, respectively. To test the applicability of PWV for clinical use, a multiple regression equation of PWV derived from these three variables was then applied to male patients with hypertension (n=53), hyperlipidaemia (n=35) or hyperglycaemia (n=39). The results suggest that the multiple regression equation of PWV is an indicator that discriminates between these patient categories and healthy men.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/s004210050644
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