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  • Keywords: Actinomadura; pravastatin; compactin; nutrition; vitamins  (1)
  • basis method  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of industrial microbiology and biotechnology 22 (1999), S. 78-79 
    ISSN: 1476-5535
    Keywords: Keywords: Actinomadura; pravastatin; compactin; nutrition; vitamins
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Actinomadura sp strain 2966, which converts compactin to pravastatin, requires vitamins to support its growth. Addition of folic acid, thiamine and cyanocobalamine allowed growth in chemically-defined medium. Cells grown in a chemically-defined medium were as capable of converting compactin to pravastatin as cells grown in a complex medium.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Mathematical geology 27 (1995), S. 105-127 
    ISSN: 1573-8868
    Keywords: closed data ; log-ratio ; basis method ; oil field ; kriging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Mathematics
    Notes: Abstract A regionalized composition is a random vector function whose components are positive and sum to a constant at every point of the sampling region. Consequently, the components of a regionalized composition are necessarily spatially correlated. This spatial dependence—induced by the constant sum constraint—is a spurious spatial correlation and may lead to misinterpretations of statistical analyses. Furthermore, the cross-covariance matrices of the regionalized composition are singular, as is the coefficient matrix of the cokriging system of equations. Three methods of performing estimation or prediction of a regionalized composition at unsampled points are discussed: (1) the direct approach of estimating each variable separately; (2) the basis method, which is applicable only when a random function is available that can he regarded as the size of the regionalized composition under study; (3) the logratio approach, using the additive-log-ratio transformation proposed by J. Aitchison, which allows statistical analysis of compositional data. We present a brief theoretical review of these three methods and compare them using compositional data from the Lyons West Oil Field in Kansas (USA). It is shown that, although there are no important numerical differences, the direct approach leads to invalid results, whereas the basis method and the additive-log-ratio approach are comparable.
    Type of Medium: Electronic Resource
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