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  • Kontrastmittel  (2)
  • Magnification radiography  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Fracture healing: direct magnification versus conventional radiography (1994)
    Springer
    European radiology 4 (1994), S. 341-346 
    Details
    ISSN: 1432-1084
    Keywords: Fracture healing ; Magnification radiography ; Roentgen technique
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The aim of the study was to evaluate the potential of magnification radiography in diagnosing fracture healing and assessing its complications. Seventy-three patients with fractures or who had undergone osteotomy were radiographed with both conventional (non-magnified) and magnification (5-fold) techniques. Since 10 patients were radiographed twice and 1 three times, 83 radiographs using each technique were obtained. All radiographs were analysed and the findings correlated with the patients' follow-up studies. The microfocal X-ray unit used for magnification radiography had a focal spot size of 20–130 μm. As an imaging system, digital luminescence radiography was employed with magnification, while normal film-screen systems were used with conventional radiography. Manification radiography proved superior to conventional radiography in 47% of cases: endosteal and periosteal callus formations were sen earlier and better in 26 cases, and osseous union could be evaluated with greater certainty in 33 cases. In 49% of cases magnification radiography was equal and in 4% inferior to conventional radiography. Additionally an “inter-observer analysis” was carried out. Anatomical and pathological structures were classified into one of four grades. Results were significantly (P 〈 0.01) better using magnification radiography. We conclude that the magnification technique is a good method for monitoring fracture healing in its early stages.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00599068
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Neue MR-Kontrastmittel in der Leberdiagnostik Erste klinische Ergebnisse mit hepatobiliärem Eovist® (Gadolinium-EOB-DTPA) und RES-spezifischem Resovist® (SH U 555 A) (1996)
    Springer
    Der Radiologe 36 (1996), S. 124-133 
    Details
    ISSN: 1432-2102
    Keywords: Schlüsselwörter Leber ; MRT ; Kontrastmittel ; Resovist® ; Eovist® ; Key words Liver ; MRI ; Contrast agents ; Resovist ; Eovist
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary The purpose of this work is to describe our initial clinical experience (in 66 patients) with Resovist and Eovist, two new liver-specific MR contrast agents. We focus our report on safety aspects, dose finding, and optimization of technical parameters. Both contrast agents were well tolerated and improved the detectability of focal liver lesions. With Resovist, postcontrast MRI may be started as early as 10 min following injection. The dose of 8 μmol Fe/kg bodyweight was sufficient to achieve diagnostic tumor-liver contrast levels. Since Eovist can also be administered as a bolus, dynamic enhance- ment patterns may be studied for tumor characterization as well. Breath-hold T 1-weighted FLASH images were superior to other T 1-weighted techniques with and without fat saturation.
    Notes: Zusammenfassung In der vorliegenden Arbeit werden erste klinische Ergebnisse (66 Patienten) der für die Leberbildgebung entwickelten Kontrastmittel Resovist® und Eovist® vorgestellt. Es wurden Sicherheitsaspekte, Dosierungsfragen und die optimale Untersuchungstechnik am Beispiel fokaler Leberläsionen untersucht. Beide „leberspezifischen“ Kontrastmittel zeigten bei guter Verträglichkeit eine Verbesserung des Nachweises fokaler Leberläsionen. Die Untersuchung mit Resovist® kann bereits 10 min nach der Kontrastmittelinjektion erfolgen. Mit einer Dosis von 8 μmol Fe/kg Körpergewicht konnte eine ausreichender Tumor-Leber-Kontrast erzielt werden. Da Eovist® zusätzlich im Bolus injiziert werden kann, ergeben sich neben dem Nachweis fokaler Leberläsionen Möglichkeiten der Charakterisierung durch Analyse der Perfusionsmuster. Atemgehaltene T 1-gewichtete FLASH-Sequenzen waren sonstigen T 1-gewichteten Sequenzen ohne und mit Fettgesättigung überlegen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001170050049
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Magnetresonanztomographie ohne und mit Gadolinium-DTPA zur Beurteilung von Nierentransplantaten (1997)
    Springer
    Der Radiologe 37 (1997), S. 225-232 
    Details
    ISSN: 1432-2102
    Keywords: Schlüsselwörter Magnetresonanztomographie ; Nierentransplantate ; Kontrastmittel ; Key words MR imaging ; Renal allografts ; Contrast medium
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Purpose: To determine the value of MR imaging in differentiating the various causes of human renal allograft dysfunction. Methods: A total of 123 human renal allografts (normal n = 20, acute rejection n = 57, acute tubular necrosis n = 14, interstitial fibrosis n = 11, chronic allograft glomerulopathy n = 11, cyclosporine nephrotoxicity n = 3, cortical necrosis n = 7) were investigated by means of MR imaging. Axial T1-weighted spin-echo images and coronal T1-weighted gradient-echo images were obtained before and after Gd-DTPA injection. Diagnostic parameters included corticomedullary contrast and allograft size and shape on the pre-contrast sequences. Results: None of the diagnostic parameters used could differentiate among the various diagnostic groups. Diagnosis of cortical necrosis could be made only on post-contrast scans. Contrast-enhanced scans were superior to pre-contrast images in detection of focal allograft lesions. Otherwise, contrast-enhanced scans did not provide any more information than pre-contrast studies. Spin-echo and gradient-echo sequences displayed the same diagnostic value. Conclusions: MR imaging has a limited value in differentiating the various causes of renal allograft dysfunction.
    Notes: Zusammenfassung Um den Stellenwert der MRT bei der Klärung der Fehlfunktion von Nierentransplantaten zu untersuchen, wurden 123 menschliche Nierentransplantate (unauffällig: n = 20, akute Rejektion: n = 57, akute tubuläre Nekrose: n = 14, interstitielle Fibrose: n = 11, Transplantatglomerulopathie: n = 11, Cyclosporinschaden: n = 3, kortikale Nekrose: n = 7) MR-tomographiert. An einem 1,5-T-Gerät wurden axiale T1-gewichtete Spinecho- und koronare T1-gewichtete Gradientenechoaufnahmen vor und nach Gabe von Gd-DTPA akquiriert. Als Beurteilungskriterien wurden der kortikomedulläre Kontrast sowie die Größe und Form des Transplantatorganes in der Nativuntersuchung herangezogen. Keines der Kriterien ermöglichte die Differenzierung der verschiedenen Diagnosegruppen. Abgesehen von der kortikalen Nekrose, die nur anhand der kontrastmittelunterstützten Sequenzen erkennbar war, lieferte die Gd-DTPA-Applikationen für die Differenzierung der verschiedenen parenchymalen Komplikationen keine Zusatzinformationen. Beim Nachweis fokaler Parenchymläsionen war die Kontrastmittelserie der Nativuntersuchungen überlegen. Die Spinecho- und Gradientenechoaufnahmen führten zu ähnlichen Resultaten. Schlußfolgernd kann davon ausgegangen werden, daß die statische MRT bei der Klärung der Fehlfunktion einer Transplantatniere eine untergeordnete Rolle spielt.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001170050203
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Imaging of bone tumors: evaluation of direct magnification radiography (1996)
    Springer
    Skeletal radiology 25 (1996), S. 441-447 
    Details
    ISSN: 1432-2161
    Keywords: Key words Bone neoplasms ; diagnosis ; Magnification radiography ; Bones ; radiography ; Radiography ; comparative studies ; Radiography ; technology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Objective. To evaluate the potentials of magnification radiography as compared with conventional radiography in diagnosing bone tumors. Design and patients. Sixty-two patients with primary bone tumors and tumorlike lesions underwent radiography with both conventional (non-magnified) and magnification (fivefold) techniques. All radiographs were analyzed by four radiologists and the findings correlated with the histopathology findings. The microfocal X-ray unit used for magnification radiography had a focal spot size of 20–130 μm. Digital luminescence radiography was employed with magnification, while normal film-screen systems were used with conventional radiography. Results. The diagnosis of benign and malignant lesions as well as the individual tumor diagnosis were determined with higher accuracy using magnification compared with conventional radiography (88% vs 75% and 71% vs 52%, p〈0.01). Margins of destruction, periosteal reactions and matrix patterns were evaluated with higher certainty by all of the radiologists (p〈0.01). Conclusion. Magnification radiography may improve the evaluation and diagnosis of bone tumors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002560050112
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    Paper (German National Licenses)
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