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    Electronic Resource
    Electronic Resource
    Activity of glutathione-S-transferase in rat liver and kidneys after administration of lead or cadmium (1992)
    Springer
    Archives of toxicology 66 (1992), S. 365-367 
    Details
    ISSN: 1432-0738
    Keywords: Glutathione-S-transferase ; Rats ; Lead ; Cadmium
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The influence of an acute dose of lead nitrate or cadmium chloride on the activity of glutathione-S-trans-ferase (GST) was investigated in rats. CdCl2 (10 Μmol/kg) did not influence the enzyme activity in either organ. In contrast Pb(NO3)2 (100 Μmol/kg) caused a significant increase of GST activity in both organs. SDS polyacrylamide gel electrophoresis (SDS-PAGE) showed that in liver the activity enhancement is due mainly to the induction of the isoenzyme GST 7-7, while in the kidneys the activity of all the isoenzymes is increased.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01973633
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